Chloroquine and sulfadoxine–pyrimethamine resistance in Sub-Saharan Africa—A review
Malaria is a great concern for global health and accounts for a large amount of morbidity and
mortality, particularly in Africa, with sub-Saharan Africa carrying the greatest burden of the …
mortality, particularly in Africa, with sub-Saharan Africa carrying the greatest burden of the …
Is Nigeria winning the battle against malaria? Prevalence, risk factors and KAP assessment among Hausa communities in Kano State
S Dawaki, HM Al-Mekhlafi, I Ithoi, J Ibrahim… - Malaria journal, 2016 - Springer
Background Malaria is one of the most severe global public health problems worldwide,
particularly in Africa, where Nigeria has the greatest number of malaria cases. This …
particularly in Africa, where Nigeria has the greatest number of malaria cases. This …
Molecular analysis of bio-makers of chloroquine resistance in Plasmodium falciparum isolate from Gombe local government area, Gombe State, Nigeria
I Muhammad, PM Sale, MK Salisu… - Cellular, Molecular …, 2022 - cmbr-journal.com
Chloroquine was one of the most cheapest and effective chemotherapeutic drugs for
Plasmodium falciparum-malaria, but for a long, the drug has been officially withdrawn in …
Plasmodium falciparum-malaria, but for a long, the drug has been officially withdrawn in …
Antimalarial drug resistance in the Central and Adamawa regions of Cameroon: Prevalence of mutations in P. falciparum crt, Pfmdr1, Pfdhfr and Pfdhps genes
AGB Tuedom, EM Sarah-Matio, CEE Moukoko… - PLoS …, 2021 - journals.plos.org
The spread of Plasmodium falciparum resistant parasites remains one of the major
challenges for malaria control and elimination in Sub Saharan Africa. Monitoring of …
challenges for malaria control and elimination in Sub Saharan Africa. Monitoring of …
The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of pfmdr1 86Y and pfcrt …
Abstract Background The majority of Plasmodium falciparum malaria cases in Africa are
treated with the artemisinin combination therapies artemether-lumefantrine (AL) and …
treated with the artemisinin combination therapies artemether-lumefantrine (AL) and …
Return of chloroquine sensitivity to Africa? Surveillance of African Plasmodium falciparum chloroquine resistance through malaria imported to China
F Lu, M Zhang, RL Culleton, S Xu, J Tang, H Zhou… - Parasites & vectors, 2017 - Springer
Background Chloroquine (CQ) was the cornerstone of anti-malarial treatment in Africa for
almost 50 years, but has been widely withdrawn due to the emergence and spread of …
almost 50 years, but has been widely withdrawn due to the emergence and spread of …
Analysis of Plasmodium falciparum Pfcrt and Pfmdr1 genes in parasite isolates from asymptomatic individuals in Southeast Nigeria 11 years after withdrawal of …
MN Ikegbunam, CN Nkonganyi, BN Thomas… - Malaria Journal, 2019 - Springer
Background A reversal of chloroquine (CQ) resistance following a period of withdrawal has
raised the possibility of its re-introduction. This study evaluated the current prevalence of …
raised the possibility of its re-introduction. This study evaluated the current prevalence of …
[HTML][HTML] Nigeria end malaria council: What to expect
Abstract Following the World Health Organization 2021 report of Nigeria being the leading
country among the four African countries responsible for half of the malaria mortality all over …
country among the four African countries responsible for half of the malaria mortality all over …
Plasmodium falciparum multidrug resistance gene-1 polymorphisms in Northern Nigeria: implications for the continued use of artemether-lumefantrine in the region
Background The analysis of single nucleotide polymorphism (SNPs) in drug-resistance
associated genes is a commonly used strategy for the surveillance of anti-malarial drug …
associated genes is a commonly used strategy for the surveillance of anti-malarial drug …
Antimalarial drug resistance profiling of Plasmodium falciparum infections in Ghana using molecular inversion probes and next-generation sequencing
ABSTRACT A key drawback to monitoring the emergence and spread of antimalarial drug
resistance in sub-Saharan Africa is early detection and containment. Next-generation …
resistance in sub-Saharan Africa is early detection and containment. Next-generation …