Furo [3, 2-c] coumarins carrying carbon substituents at C-2 and/or C-3. Isolation, biological activity, synthesis and reaction mechanisms

I Cortés, LJ Cala, ABJ Bracca, TS Kaufman - RSC advances, 2020 - pubs.rsc.org
The isolation, biological activity and synthesis of natural furo [3, 2-c] coumarins are
presented, covering mainly the developments in the last 35 years. The most relevant …

Discovery of pyran annulated heterocyclic scaffolds linked to carboxamide fragments: Anticancer evaluation, topoisomerase I/II, tyrosine kinase receptor inhibition and …

AM Fouda, RA El-Eisawy, MAA El-Nassag… - Journal of Molecular …, 2024 - Elsevier
A class of 4H-benzo [h] chromene (4a-h) and 1H-benzo [f] chromene (6a-h) derivatives
linked to carboxamide/carbothioamide at the 3/2-positions were designed and synthesized …

[PDF][PDF] Strongly proton exchanged montmorillonite K10 (H+-Mont) as a solid acid catalyst for highly efficient and environmental benign synthesis of biscoumarins via …

B Zeynizadeh, S Rahmani, S Ilkhanizadeh - Polyhedron, 2019 - academia.edu
In this study, synthesis of micro/meso porous acid-activated montmorillonite K10 (H+-Mont)
was carried out by the activation of Na+-montmorillonite with HCl (4 M) at the controlled …

Synthesis of 9-Hydroxy-1H-Benzo[f]chromene Derivatives with Effective Cytotoxic Activity on MCF7/ADR, P-Glycoprotein Inhibitors, Cell Cycle Arrest and Apoptosis …

FF Albalawi, MAA El-Nassag, RA El-Eisawy… - International Journal of …, 2022 - mdpi.com
β-Enaminonitriles bearing 9-hydroxy-1 H-benzo [f] chromene moiety was synthesized. The
targeted compounds were evaluated for their anti-proliferative activity against three human …

Phellinus baumii Polyphenol: A Potential Therapeutic Candidate against Lung Cancer Cells

X Liu, S Cui, C Dan, W Li, H Xie, C Li, L Shi - International Journal of …, 2022 - mdpi.com
Phellinus baumii, a fungus that grows on mulberry trees and is used in traditional Chinese
medicine, exerts therapeutic effects against various diseases, including cancer …

A proficient microwave synthesis with structure elucidation and the exploitation of the biological behavior of the newly halogenated 3-amino-1H-benzo [f] chromene …

AM Fouda, RM Okasha, FF Alblewi, A Mora, TH Afifi… - Bioorganic …, 2020 - Elsevier
In our endeavors to develop novel and powerful agents with antiproliferative activities, a
series of β-enamionitriles, linked to the 8-bromo-1H-benzo [f] chromene moieties (4a-m) …

Synthesis, cytotoxic activity, crystal structure, DFT, molecular docking study of some heterocyclic compounds incorporating benzo [f] chromene moieties

HKA El-Mawgoud, HAM Radwan, AM Fouda… - Journal of Molecular …, 2022 - Elsevier
Abstract The β-enaminonitrile (1) interacted with 1, 1, 1-triethoxymethane in the presence or
absence of acetic anhydride under reflux resulted in the formation of an imidate (2a, b) …

In Vitro andIn Vivo Experimental Model-based Approaches for Investigating Anti-inflammatory Properties of Coumarins

SV Gagliotti Vigil de Mello… - Current Medicinal …, 2018 - ingentaconnect.com
Background: Coumarins are polyphenolic compounds that are often used to treat
inflammatory conditions in complementary and alternative medicine. Objective: In this study …

Synthetic aspects and Biological Studies of some Heterocycles.

D Gandhi, P Kalal, S Agarwal - Chemistry & Biology Interface, 2017 - search.ebscohost.com
Heterocyclic chemistry is a key branch of chemistry dealing with synthesis, properties and
applications of heterocycles. Heterocycles have enormous potential as the most promising …

CuCl2-catalyzed NO bond cleavage of oxime esters: Approach to imidazoheterocycles and furo [3, 2-c] chromenyl fused imidazoles

SK Gudimella, A Kaur, R Kumar, S Samanta - Tetrahedron Letters, 2020 - Elsevier
An articulate approach to a diverse set of imidazoheterocycles in good to high yields via a
copper-catalyzed aza-annulation of several oxime esters with a group of 2-amino-azaarenes …