Embryonic stem cells (ESCs) are derived from the inner cell mass of preimplantation
blastocysts. For decades, attempts to efficiently derive ESCs in animal livestock species …

Background A random multiple-regression model that simultaneously fit all allele
substitution effects for additive markers or haplotypes as uncorrelated random effects was …

Background Mathematical models are needed for the design of breeding programs using
genomic prediction. While deterministic models for selection on pedigree-based estimates of …

Bayesian multiple-regression methods incorporating different mixture priors for marker
effects are used widely in genomic prediction. Improvement in prediction accuracies from …

This study aims at characterizing the asymptotic behavior of genomic prediction R 2 as the
size of the reference population increases for common or rare QTL alleles through …

In breeding programs, genetic evaluations can be performed using phenotypic information
from the selection candidates per se or from relatives to obtain breeding values (EBV) by the …

The vast amount of sequence data generated to analyze complex traits is posing new
challenges in terms of the analysis and interpretation of the results. Although simulation is a …

Modern animal breeding programmes are constantly evolving with advances in breeding
theory, biotechnology and genetics. Surprisingly, there seems to be no generally accepted …

Simulation can be an efficient approach to design, evaluate, and optimize breeding
programs. In the era of modern agriculture, breeding programs can benefit from a simulator …

Modeling covariance structure based on genetic similarity between pairs of relatives plays
an important role in evolutionary, quantitative and statistical genetics. Historically, genetic …