Oxidative stress, protein damage and repair in bacteria

B Ezraty, A Gennaris, F Barras, JF Collet - Nature Reviews Microbiology, 2017 - nature.com
Oxidative damage can have a devastating effect on the structure and activity of proteins, and
may even lead to cell death. The sulfur-containing amino acids cysteine and methionine are …

Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

B Halliwell, M Whiteman - British journal of pharmacology, 2004 - Wiley Online Library
Free radicals and other reactive species (RS) are thought to play an important role in many
human diseases. Establishing their precise role requires the ability to measure them and the …

The oxidative environment and protein damage

MJ Davies - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2005 - Elsevier
Proteins are a major target for oxidants as a result of their abundance in biological systems,
and their high rate constants for reaction. Kinetic data for a number of radicals and non …

Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance

S Lee, SM Kim, RT Lee - Antioxidants & redox signaling, 2013 - liebertpub.com
The thioredoxin (Trx) system is one of the central antioxidant systems in mammalian cells,
maintaining a reducing environment by catalyzing electron flux from nicotinamide adenine …

Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid β-peptide-associated free radical …

DA Butterfield, CM Lauderback - Free Radical Biology and Medicine, 2002 - Elsevier
Amyloid β-peptide (Aβ) is heavily deposited in the brains of Alzheimer's disease (AD)
patients, and free radical oxidative stress, particularly of neuronal lipids and proteins, is …

Role of sulfur chirality in the chemical processes of biology

R Bentley - Chemical Society Reviews, 2005 - pubs.rsc.org
Chiral structures profoundly influence chemical and biological processes. While chiral
carbon biomolecules have received much attention, chirality is also possible in certain sulfur …

Oxidative stress and protein aggregation during biological aging

TC Squier - Experimental gerontology, 2001 - Elsevier
Biological aging is a fundamental process that represents the major risk factor with respect
to the development of cancer, neurodegenerative, and cardiovascular diseases in …

Protein damage, repair and proteolysis

N Chondrogianni, I Petropoulos, S Grimm… - Molecular aspects of …, 2014 - Elsevier
Proteins are continuously affected by various intrinsic and extrinsic factors. Damaged
proteins influence several intracellular pathways and result in different disorders and …

Regulation of cell function by methionine oxidation and reduction

T Hoshi, SH Heinemann - The Journal of physiology, 2001 - Wiley Online Library
Reactive oxygen species (ROS) are generated during normal cellular activity and may exist
in excess in some pathophysiological conditions, such as inflammation or reperfusion injury …

Staphylococcal response to oxidative stress

R Gaupp, N Ledala, GA Somerville - Frontiers in cellular and infection …, 2012 - frontiersin.org
Staphylococci are a versatile genus of bacteria that are capable of causing acute and
chronic infections in diverse host species. The success of staphylococci as pathogens is due …