Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation
of the spatial localization of transcripts and related analyses in various applications for …

The proper functioning of diverse biological systems depends on the spatial organization of
their cells, a critical factor for biological processes like shaping intricate tissue functions and …

Determining mutational landscapes in a spatial context is essential for understanding
genetically heterogeneous cell microniches. Current approaches, such as Multiple …

Cells do not live in a vacuum, but in a milieu defined by cell–cell communication that can be
measured via emerging high-resolution spatial transcriptomics approaches. However …

Technologies to decipher cellular biology, such as bulk sequencing technologies and single-
cell sequencing technologies, have greatly assisted novel findings in tumor biology. Recent …

Spatial transcriptomics, which is capable of both measuring all gene activity in a tissue
sample and mapping where this activity occurs, is vastly improving our understanding of …

Abstract Glioblastoma (GBM) comprises 45.6% of all primary malignant brain cancers and is
one of the most common and aggressive intracranial tumors in adults. Intratumoral …

Individual cancer cells are not equal but are organized into a cellular hierarchy in which only
a rare few leukemia cells can self-renew in a manner reminiscent of the characteristic stem …

High-quality, straightforward single-cell RNA sequencing (RNA-seq) with spatial resolution
remains challenging. Here, we developed DRaqL (direct RNA recovery and quenching for …

Beyond transcription, RNA molecules are enzymatically modified to influence the biological
functions of living organisms. The term “epitranscriptomics” describes the changes in RNA …