Counterfeit drugs: analytical techniques for their identification

R Martino, M Malet-Martino, V Gilard… - Analytical and …, 2010 - Springer
In recent years, the number of counterfeit drugs has increased dramatically, including not
only “lifestyle” products but also vital medicines. Besides the threat to public health, the …

Arthemeter-loaded lipid nanoparticles produced by modified thin-film hydration: Pharmacokinetics, toxicological and in vivo anti-malarial activity

NP Aditya, S Patankar, B Madhusudhan… - European Journal of …, 2010 - Elsevier
Artemether-loaded lipid nanoparticles (ARM-LNP) composed of 5%(w/v) lipid mass were
produced by a modified thin-film hydration method using glyceryl trimyristate (solid lipid) and …

Validated RP-HPLC method for simultaneous determination and quantification of chlorpheniramine maleate, paracetamol and caffeine in tablet formulation

A Acheampong, WO Gyasi, G Darko, J Apau… - Springerplus, 2016 - Springer
Chlorpheniramine maleate–paracetamol–caffeine tablet formulation is one of the common
over-the-counter drugs used for the treatment of cold and cough. A reversed-phase high …

Artemether and lumefantrine dissolving microneedle patches with improved pharmacokinetic performance and antimalarial efficacy in mice infected with Plasmodium …

F Volpe-Zanutto, LT Ferreira, AD Permana… - Journal of controlled …, 2021 - Elsevier
Malaria affects more than 200 million people annually around the world, killing a child every
2 min. Artemether (ART) and lumefantrine (LUM) are the gold standard choice to treat …

Development of hot melt co-formulated antimalarial solid dispersion system in fixed dose form (ARLUMELT): Evaluating amorphous state and in vivo performance

R Fule, D Dhamecha, M Maniruzzaman, A Khale… - International journal of …, 2015 - Elsevier
The aim of this study was to investigate the industrial feasibility of developing a co-
formulated solid dispersion (SD) containing two antimalarial drugs artemether (ARTM) and …

Molecularly imprinted polymeric coatings for sensitive and selective gravimetric detection of artemether

U Arshad, A Mujahid, P Lieberzeit, A Afzal, SZ Bajwa… - RSC …, 2020 - pubs.rsc.org
Monitoring antimalarial drugs is necessary for clinical assays, human health, and routine
quality control practices in pharmaceutical industries. Herein, we present the development of …

Green analytical methods of antimalarial artemether-lumefantrine analysis for falsification detection using a low-cost handled NIR spectrometer with DD-SIMCA and …

M Yabré, L Ferey, AK Sakira, C Bonmatin, C Fauré… - Molecules, 2020 - mdpi.com
Two green analytical approaches have been developed for the analysis of antimalarial fixed
dose tablets of artemether and lumefantrine for quality control. The first approach consisted …

Development of simplified HPLC methods for the detection of counterfeit antimalarials in resource-restraint environments

L Hoellein, U Holzgrabe - Journal of Pharmaceutical and Biomedical …, 2014 - Elsevier
Regular quality control and post-marketing surveillance of pharmaceuticals has been a
critical challenge for countries of the developing world ever since. Counterfeit and …

Liquid chromatography–tandem mass spectrometry for the simultaneous quantitation of artemether and lumefantrine in human plasma: Application for a …

IC César, JA de Aquino Ribeiro… - … of pharmaceutical and …, 2011 - Elsevier
A liquid chromatography–electrospray ionization tandem mass spectrometry (HPLC–ESI-
MS/MS) method for the simultaneous quantitation of artemether and lumefantrine in human …

Simultaneous quantitation of chloroquine and primaquine by UPLC-DAD and comparison with a HPLC-DAD method

TA Miranda, PHR Silva, GA Pianetti, IC César - Malaria Journal, 2015 - Springer
Background Chloroquine and primaquine are the first-line treatment recommended by World
Health Organization for malaria caused by Plasmodium vivax. Since the problem of …