γδ T cells in tissue physiology and surveillance

JC Ribot, N Lopes, B Silva-Santos - Nature Reviews Immunology, 2021 - nature.com
Abstract γδ T cells are a unique T cell subpopulation that are rare in secondary lymphoid
organs but enriched in many peripheral tissues, such as the skin, intestines and lungs. By …

The third international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation

CN Kotton, D Kumar, AM Caliendo, S Huprikar… - …, 2018 - journals.lww.com
Despite recent advances, cytomegalovirus (CMV) infections remain one of the most common
complications affecting solid organ transplant recipients, conveying higher risks of …

Key features of gamma-delta T-cell subsets in human diseases and their immunotherapeutic implications

M Lawand, J Déchanet-Merville… - Frontiers in …, 2017 - frontiersin.org
The unique features of gamma-delta (γδ) T cells, related to their antigen recognition
capacity, their tissue tropism, and their cytotoxic function, make these cells ideal candidates …

Immunity, tolerance and autoimmunity in the liver: A comprehensive review

DG Doherty - Journal of autoimmunity, 2016 - Elsevier
The hepatic immune system is constantly exposed to a massive load of harmless dietary and
commensal antigens, to which it must remain tolerant. Immune tolerance in the liver is …

Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection

S Ravens, C Schultze-Florey, S Raha, I Sandrock… - Nature …, 2017 - nature.com
To investigate how the human γδ T cell pool is shaped during ontogeny and how it is
regenerated after transplantation of hematopoietic stem cells (HSCs), we applied an RNA …

γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ+/CD19+ lymphocytes

I Airoldi, A Bertaina, I Prigione, A Zorzoli… - Blood, The Journal …, 2015 - ashpublications.org
We prospectively assessed functional and phenotypic characteristics of γδ T lymphocytes up
to 7 months after HLA-haploidentical hematopoietic stem cell transplantation (haplo-HSCT) …

Human cytomegalovirus latency and reactivation in allogeneic hematopoietic stem cell transplant recipients

L Stern, B Withers, S Avdic, D Gottlieb… - Frontiers in …, 2019 - frontiersin.org
Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …

Tissue adaptations of memory and tissue-resident gamma delta T cells

C Khairallah, TH Chu, BS Sheridan - Frontiers in immunology, 2018 - frontiersin.org
Epithelial and mucosal barriers are critical interfaces physically separating the body from the
outside environment and are the tissues most exposed to microorganisms and potential …

Human cytomegalovirus immunity and immune evasion

SE Jackson, GM Mason, MR Wills - Virus research, 2011 - Elsevier
Human cytomegalovirus (HCMV) infection induces both innate immune responses including
Natural Killer cells as well as adaptive humoral and cell mediated (CD4+ helper, CD8+ …

Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor

CR Willcox, V Pitard, S Netzer, L Couzi, M Salim… - Nature …, 2012 - nature.com
T cells bearing γδ T cell antigen receptors (TCRs) function in lymphoid stress surveillance.
However, the contribution of γδ TCRs to such responses is unclear. Here we found that the …