The microbial damage and host response framework: lesson learned from pathogenic survival trajectories and immunoinflammatory responses of Talaromyces …

K Pruksaphon, A Amsri, J Jeenkeawpieam… - Frontiers in …, 2024 - frontiersin.org
The adverse outcomes of fungal infection in mammalian hosts depend on the complex
interactions between the host immune system and pathogen virulence-associated traits. The …

[HTML][HTML] Extracellular vesicles derived from Talaromyces marneffei contain immunogenic compounds and modulate THP-1 macrophage responses

K Pruksaphon, A Amsri, P Thammasit… - Frontiers in …, 2023 - frontiersin.org
Pathogenic eukaryotes including fungi release extracellular vesicles (EVs) which are
composed of a variety of bioactive components, including peptides, nucleic acids …

Functional characterization of macrophages and change of Th1/Th2 balance in patients with pythiosis after Pythium insidiosum antigen immunotherapy

S Medhasi, N Sangphech, N Permpalung… - Scientific reports, 2024 - nature.com
There has been limited research into the role of the Pythium insidiosum antigen (PIA) in
modulating immune response in patients with pythiosis. This study investigated the balance …

Talaromyces marneffei infection and complicate manifestation of respiratory system in HIV-negative children

Q Yang, Y Wu, X Li, Y Bao, W Wang, Y Zheng - BMC Pulmonary Medicine, 2023 - Springer
Background Respiratory symptoms are the earliest clinical manifestation of Talaromyces
marneffei (TM) infection. In this study, we aimed to improve the early identification of TM …

Differential innate immune responses of human macrophages and bronchial epithelial cells against Talaromyces marneffei

YP Tan, CC Tsang, KF Chan, SL Fung, KH Kok… - Msphere, 2023 - Am Soc Microbiol
Talaromyces marneffei is a thermally dimorphic fungal pathogen endemic in Southeast Asia.
As inhalation of airborne conidia is believed as the major infection route, airway epithelial …