[HTML][HTML] The future of pharmaceutical manufacturing sciences
J Rantanen, J Khinast - Journal of pharmaceutical sciences, 2015 - Elsevier
The entire pharmaceutical sector is in an urgent need of both innovative technological
solutions and fundamental scientific work, enabling the production of highly engineered …
solutions and fundamental scientific work, enabling the production of highly engineered …
Latent variable modeling to assist the implementation of Quality-by-Design paradigms in pharmaceutical development and manufacturing: A review
The introduction of the Quality-by-Design (QbD) initiative and of the Process Analytical
Technology (PAT) framework by the Food and Drug Administration has opened the route to …
Technology (PAT) framework by the Food and Drug Administration has opened the route to …
A perspective on Quality-by-Control (QbC) in pharmaceutical continuous manufacturing
Abstract The Quality-by-Design (QbD) guidance issued by the US Food and Drug
Administration (FDA) has catalyzed the modernization of pharmaceutical manufacturing …
Administration (FDA) has catalyzed the modernization of pharmaceutical manufacturing …
Using residence time distributions (RTDs) to address the traceability of raw materials in continuous pharmaceutical manufacturing
W Engisch, F Muzzio - Journal of pharmaceutical innovation, 2016 - Springer
Continuous processing in pharmaceutical manufacturing is a relatively new approach that
has generated significant attention. While it has been used for decades in other industries …
has generated significant attention. While it has been used for decades in other industries …
An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process
F Boukouvala, V Niotis, R Ramachandran… - Computers & chemical …, 2012 - Elsevier
Manufacturing of powder-based products is a focus of increasing research in the recent
years. The main reason is the lack of predictive process models connecting process …
years. The main reason is the lack of predictive process models connecting process …
An engineering study on the enhanced control and operation of continuous manufacturing of pharmaceutical tablets via roller compaction
A novel manufacturing strategy based on continuous processing integrated with online
monitoring tools coupled with efficient automatic feedback control system is highly desired …
monitoring tools coupled with efficient automatic feedback control system is highly desired …
System-wide hybrid MPC–PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction
The next generation of QbD based pharmaceutical products will be manufactured through
continuous processing. This will allow the integration of online/inline monitoring tools …
continuous processing. This will allow the integration of online/inline monitoring tools …
A systematic framework for onsite design and implementation of a control system in a continuous tablet manufacturing process
A novel manufacturing strategy based on continuous processing integrated with
online/inline monitoring tools coupled with an advanced control system is highly desired for …
online/inline monitoring tools coupled with an advanced control system is highly desired for …
Modeling of particulate processes for the continuous manufacture of solid-based pharmaceutical dosage forms
AJ Rogers, A Hashemi, MG Ierapetritou - Processes, 2013 - mdpi.com
The objective of this work is to present a review of computational tools and models for
pharmaceutical processes, specifically those for the continuous manufacture of solid dosage …
pharmaceutical processes, specifically those for the continuous manufacture of solid dosage …
Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review
M Teżyk, B Milanowski, A Ernst… - Drug development and …, 2016 - Taylor & Francis
Context: Continuous processing is an innovative production concept well known and
successfully used in other industries for many years. The modern pharmaceutical industry is …
successfully used in other industries for many years. The modern pharmaceutical industry is …