Macrophage polarization in physiological and pathological pregnancy

Y Yao, XH Xu, L Jin - Frontiers in immunology, 2019 - frontiersin.org
The immunology of pregnancy is complex and poorly defined. During the complex process
of pregnancy, macrophages secrete many cytokines/chemokines and play pivotal roles in …

CCL2: An important cytokine in normal and pathological pregnancies: A review

Z Lin, JL Shi, M Chen, ZM Zheng, MQ Li… - Frontiers in …, 2023 - frontiersin.org
CC motif ligand 2 (CCL2), also known as monocytic chemotactic protein 1 (MCP-1), is an
integral chemotactic factor which recruits macrophages for the immune response. Together …

Decreased B7-H3 promotes unexplained recurrent miscarriage via RhoA/ROCK2 signaling pathway and regulates the secretion of decidual NK cells

D Zhang, Y Yu, C Ding, R Zhang, T Duan… - Biology of …, 2023 - academic.oup.com
The cause for at least 50% of recurrent miscarriages is unclear, which is defined as
unexplained recurrent miscarriages. The B7-H1 (PD-L1), a molecule of the B7 family …

Updates of placental macrophages: Origins, molecular markers, functions, and related diseases

H Yang, A Chelariu-Raicu, D Makri, C Ori… - Journal of Reproductive …, 2023 - Elsevier
Placental macrophages are highly heterogeneous cells with differential phenotypes and
functions defined by differential origins and modulated by the changing placental …

Potential Mechanisms of Guizhi Fuling Wan in Treating Endometriosis: An Analysis Based on TCMSP and DisGeNET Databases

JL Yee, CY Huang, YC Yu, SJ Huang - Journal of Ethnopharmacology, 2024 - Elsevier
Abstract Ethnopharmacological relevance Guizhi Fuling Wan (GFW), is a traditional Chinese
herbal formula that consists of Cinnamomi Ramulus (Guizhi), Poria Cocos (Schw.) …

Downregulation of HDAC8 expression decreases CD163 levels and promotes the apoptosis of macrophages by activating the ERK signaling pathway in recurrent …

Y Yao, F Hao, LC Tang, XH Xu… - Molecular Human …, 2020 - academic.oup.com
Recurrent spontaneous miscarriage (RSM) is a systemic disorder that has been defined as
two or more pregnancies lost before the 20th week of gestation. Although the impaired …

Transcriptomics and immunological analyses reveal a pro-angiogenic and anti-inflammatory phenotype for decidual endothelial cells

C Agostinis, E Masat, F Bossi, G Ricci… - International Journal of …, 2019 - mdpi.com
Background: In pregnancy, excessive inflammation and break down of immunologic
tolerance can contribute to miscarriage. Endothelial cells (ECs) are able to orchestrate the …

The evaluation of embryotoxicity of Ligusticum chuanxiong on mice and embryonic stem cells

H Wang, Q Bao, H Yi, Q Xia - Journal of ethnopharmacology, 2019 - Elsevier
Abstract Ethnopharmacological relevance Chuanxiong (Chuanxiong Rhizoma, CR), the
dried rhizome of Ligusticum chuanxiong Hort, has been used during pregnancy for more …

[HTML][HTML] The abortificient effects of hydroalcoholic extract of lawsonia inermis on BALB/c mice

R Esteki, S Miraj - Electronic physician, 2016 - ncbi.nlm.nih.gov
Methods This research study used an experimental methodology and was conducted in
2013 in Shahrekord, Iran. Forty female BALB/c mice (30–40 gm, 8–12 weeks old) were …

Effect of Japanese herbal Kampo medicines on live birth rate in women with recurrent pregnancy loss

D Shigemi, Y Hashimoto, N Michihata… - … of Gynecology & …, 2021 - Wiley Online Library
Objective To determine the effectiveness of Japanese Kampo medicines on the overall live
birth rate among patients with recurrent pregnancy loss (RPL) in a real‐world setting …