Environment and gene association with obesity and their impact on neurodegenerative and neurodevelopmental diseases
MT Flores-Dorantes, YE Díaz-López… - Frontiers in …, 2020 - frontiersin.org
Obesity is a multifactorial disease in which environmental conditions and several genes play
an important role in the development of this disease. Obesity is associated with …
an important role in the development of this disease. Obesity is associated with …
Alcohol, adipose tissue and lipid dysregulation
JL Steiner, CH Lang - Biomolecules, 2017 - mdpi.com
Chronic alcohol consumption perturbs lipid metabolism as it increases adipose tissue
lipolysis and leads to ectopic fat deposition within the liver and the development of alcoholic …
lipolysis and leads to ectopic fat deposition within the liver and the development of alcoholic …
Alcoholic liver disease: a new insight into the pathogenesis of liver disease
Excessive alcohol consumption contributes to a broad clinical spectrum of liver diseases,
from simple steatosis to end-stage hepatocellular carcinoma. The liver is the primary organ …
from simple steatosis to end-stage hepatocellular carcinoma. The liver is the primary organ …
Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction in a rat model of alcoholic liver disease: role of zinc deficiency
Morphological and functional alterations of hepatic mitochondria have been documented in
patients with alcoholic liver disease (ALD). Our recent study demonstrated that zinc level …
patients with alcoholic liver disease (ALD). Our recent study demonstrated that zinc level …
Alcohol and hepatocellular carcinoma: adding fuel to the flame
P Ramadori, FJ Cubero, C Liedtke, C Trautwein… - Cancers, 2017 - mdpi.com
Primary tumors of the liver represent the fifth most common type of cancer in the world and
the third leading cause of cancer-related death. Case-control studies from different countries …
the third leading cause of cancer-related death. Case-control studies from different countries …
[PDF][PDF] Adipose‐specific lipin‐1 overexpression renders hepatic ferroptosis and exacerbates alcoholic steatohepatitis in mice
Lipin‐1 is a Mg2+‐dependent phosphatidic acid phosphohydrolase involved in the
generation of diacylglycerol during synthesis of phospholipids and triglycerides. Ethanol …
generation of diacylglycerol during synthesis of phospholipids and triglycerides. Ethanol …
Alcohol, White Adipose Tissue, and Brown Adipose Tissue: Mechanistic Links to Lipogenesis and Lipolysis
According to data from the World Health Organization, there were about 3 million deaths
caused by alcohol consumption worldwide in 2016, of which about 50% were related to liver …
caused by alcohol consumption worldwide in 2016, of which about 50% were related to liver …
Gut microbiota: target for modulation of gut‐liver‐adipose tissue axis in ethanol‐induced liver disease
Consumption of alcohol (ethanol) in various forms has been an integral part of human
civilization. Since ages, it also has been an important cause of death and health impairment …
civilization. Since ages, it also has been an important cause of death and health impairment …
A review of the role of ethanol‐induced adipose tissue dysfunction in alcohol‐associated liver disease
Alcohol‐associated liver disease (AALD) encompasses a spectrum of liver diseases that
includes simple steatosis, steatohepatitis, fibrosis, and cirrhosis. The adverse effects of …
includes simple steatosis, steatohepatitis, fibrosis, and cirrhosis. The adverse effects of …
Advancements in the alcohol-associated liver disease model
L Zhu, HD Li, JJ Xu, JJ Li, M Cheng, XM Meng… - Biomolecules, 2022 - mdpi.com
Alcohol-associated liver disease (ALD) is an intricate disease that results in a broad
spectrum of liver damage. The presentation of ALD can include simple steatosis …
spectrum of liver damage. The presentation of ALD can include simple steatosis …