The formation of the follicular antrum and follicular fluid has received scant attention from
researchers, yet both are important processes in follicular development. The central …

Cellular interactions in the mammalian ovarian follicle between its germ‐line and somatic
cell components are crucial for its development and function. These interactions are …

The expansion, or mucification, of the mouse cumulus oophorus in vitro requires the
presence of an enabling factor secreted by the oocyte as well as stimulation with follicle …

Considerable challenges in engineering the female reproductive tissue are the follicle's
unique architecture, the need to recapitulate the extracellular matrix, and tissue …

A simplified culture system was developed for the in-vitro maturation of early preantral
mouse ovarian follicles. The follicles were cultured singly in 20 (μ droplets under oil in …

Anti-cancer therapy, particularly chemotherapy, damages ovarian follicles and promotes
ovarian failure. The only pharmacological means for protecting the ovaries from …

This paper is a review of the current status of technology for mammalian oocyte growth and
development in vitro. It compares and contrasts the characteristics of the various culture …

Objective To isolate intact preantral follicles from the human ovary for in vitro studies.
Procedure Premenopausal human ovary was digested by a mixture of collagenase and …

The extracellular matrix (ECM) provides a three-dimensional structure that promotes and
regulates cell adhesion and provides signals that direct the cellular processes leading to …

Chemo-and radiation therapies used to treat cancer can have the unintended effect of
making patients infertile. Clinically established fertility preservation methods, such as egg …