The comprehensive understanding and proper use of supramolecular interactions have
become critical for the development of functional materials, and so is the biomedical …

The adsorption of DNA onto gold due to affinity interactions is highly desirable for
developing low-cost, convenient and sensitive biosensors. To date, DNA–gold adsorption …

Colorimetric detection of target analytes with high specificity and sensitivity is of fundamental
importance to clinical and personalized point-of-care diagnostics. Because of their …

Epigenetic reprogramming in cancer genomes creates a distinct methylation landscape
encompassing clustered methylation at regulatory regions separated by large intergenic …

hydroxymethylcytosine (5hmC) is a key epigenetic mark in the mammalian genome that has
been proposed as a promising cancer biomarker with diagnostic and prognostic potentials …

DNA methylation as one of the most important epigenetic modifications has a critical role in
regulating gene expression and drug resistance in treating diseases such as cancer …

The chances of curing and reducing the adverse effect of cancer partly lie in early detection.
Colorimetric sensor-based technique show promising results since the target is detected …

DNA methylation occurs when a methyl group is added to a cytosine (C) residue's fifth
carbon atom, forming 5-methylcytosine (5-mC). Cancer genomes have a distinct methylation …

Facile and efficient detection of cancer cells at their preclinical stages is one of the central
challenges in cancer diagnostics. A direct, rapid, highly sensitive and specific biosensor for …

We report a simple electrochemical method referred to as “eMethylsorb” for the detection of
DNA methylation. The method relies on the base dependent affinity interaction of DNA with …