Biomarkers are of tremendous importance for the prediction, diagnosis, and observation of
the therapeutic success of common complex multifactorial metabolic diseases, such as type …

The proteins secreted by various cells (the secretomes) are a potential rich source of
biomarkers as they reflect various states of the cells at real time and at given conditions. To …

Despite intensive studies, the molecular mechanisms by which the genetic materials are
uploaded into microvesicles (MVs) are still unknown. This is the first study describing a …

Secreted proteins constitute a large and biologically important subset of proteins that are
involved in cellular communication, adhesion and migration. Yet secretomes are …

Macroautophagy, a catabolic process of cellular self-digestion, is an important tumor cell
survival mechanism and a potential target in antineoplastic therapies. Recent discoveries …

Aqueous humor (AH) is a dynamic intraocular fluid that supports the vitality of tissues that
regulate intraocular pressure. We recently discovered that extracellular nanovesicles called …

The secretome is the collection of all macromolecules secreted by a cell, and is a vital
aspect of cell–cell communication in eukaryotes. In cancer, tumour cells often display …

The cancer secretome reflects the assortment of proteins released by cancer cells.
Investigating cell secretomes not only provides a deeper knowledge of the healthy and …

Despite major improvements on the knowledge and clinical management, cancer is still a
deadly disease. Novel biomarkers for better cancer detection, diagnosis and treatment …

The differentiation of odontoblasts is initiated by the organization of differentiating
ameloblasts during tooth formation. However, the exact roles of ameloblast-derived factors …