African Americans are disproportionately affected by heart failure, with a high prevalence at
an early age. Hypertension, diabetes, obesity, and chronic kidney disease are all common in …

Objectives: ST2 and galectin-3 (Gal-3) were compared head-to-head for long-term risk
stratification in an ambulatory heart failure (HF) population on top of other risk factors …

The implantable cardioverter defibrillator (ICD) has emerged as an important treatment
option for selected patients who are at risk of sudden cardiac death. Randomized trials have …

The prognostic significance of cardiospecific troponins and natriuretic peptides in patients
with myocardial ischemia is well established, and their measurement is now endorsed by …

Background: The leading mechanisms responsible for the most prevalent and serious
cardiac injuries include myocardiocyte stretch, myocardiocyte necrosis and cardiac fibrosis …

Background Limited data exists regarding biomarker use to predict left ventricular (LV)
reverse remodeling (R2). Our aim was to examine the value of soluble ST2 (ST2), N-terminal …

Aim Between 10 and 30% of patients undergoing percutaneous coronary intervention (PCI)
have left ventricular (LV) dysfunction. We investigate the association between LV function on …

Aims The HEart function Assessment Registry Trial in Saudi Arabia (HEARTS) is a national
multicentre project, studying clinical features, management, short‐and long‐term outcomes …

42 Hallmark features of systolic heart failure are reduced contractility and impaired
metabolic 43 flexibility of the myocardium. Cardiomyocytes (CMs) with elevated deoxy ATP …

Digoxin has been a key therapeutic for heart failure and atrial tachyarrhythmias for over 200
years following Withering's groundbreaking work depicting the therapeutic benefit of the …