Applications of fourier transform ion cyclotron resonance (FT-ICR) and orbitrap based high resolution mass spectrometry in metabolomics and lipidomics

M Ghaste, R Mistrik, V Shulaev - International journal of molecular …, 2016 - mdpi.com
Metabolomics, along with other “omics” approaches, is rapidly becoming one of the major
approaches aimed at understanding the organization and dynamics of metabolic networks …

Oxidative stress and preterm birth: an integrative review

TA Moore, IM Ahmad… - Biological research for …, 2018 - journals.sagepub.com
Background: A variety of methods and measures have been used to quantify oxidative stress
in clinical studies related to preterm birth (PTB), and studies have reported conflicting …

Regulation of maternal–fetal metabolic communication

CE Bowman, Z Arany, MJ Wolfgang - Cellular and molecular life sciences, 2021 - Springer
Pregnancy may be the most nutritionally sensitive stage in the life cycle, and improved
metabolic health during gestation and early postnatal life can reduce the risk of chronic …

Metabolomics of human amniotic fluid and maternal plasma during normal pregnancy

M Orczyk-Pawilowicz, E Jawien, S Deja, L Hirnle… - PloS one, 2016 - journals.plos.org
Metabolic profiles of amniotic fluid and maternal blood are sources of valuable information
about fetus development and can be potentially useful in diagnosis of pregnancy disorders …

An immunological perspective on neonatal sepsis

B Kan, HR Razzaghian, PM Lavoie - Trends in molecular medicine, 2016 - cell.com
Despite concerted international efforts, mortality from neonatal infections remains
unacceptably high in some areas of the world, particularly for premature infants. Recent …

The metabolomic signature of the placenta in spontaneous preterm birth

S Elshenawy, SE Pinney, T Stuart, PT Doulias… - International journal of …, 2020 - mdpi.com
The placenta is metabolically active and supports the growth of the fetus. We hypothesize
that deficits in the capacity of the placenta to maintain bioenergetic and metabolic stability …

Cord blood metabolome is highly associated with birth weight, but less predictive for later weight development

C Hellmuth, O Uhl, M Standl, H Demmelmair… - Obesity facts, 2017 - karger.com
Abstract Background/Aims: Fetal metabolism may be changed by the exposure to maternal
factors, and the route to obesity may already set in utero. Cord blood metabolites might …

Following healthy pregnancy by NMR metabolomics of plasma and correlation to urine

J Pinto, AS Barros, MRM Domingues… - Journal of proteome …, 2015 - ACS Publications
This work presents the first NMR metabolomics study of maternal plasma during pregnancy,
including correlation between plasma and urine metabolites. The expected decrease in …

What have metabolomics approaches taught us about type 2 diabetes?

A Gonzalez-Franquesa, AM Burkart, E Isganaitis… - Current diabetes …, 2016 - Springer
Abstract Type 2 diabetes (T2D) is increasing worldwide, making identification of biomarkers
for detection, staging, and effective prevention strategies an especially critical scientific and …

The role of metabolomics in neonatal and pediatric laboratory medicine

M Mussap, R Antonucci, A Noto, V Fanos - Clinica Chimica Acta, 2013 - Elsevier
Metabolomics consists of the quantitative analysis of a large number of low molecular mass
metabolites involving substrates or products in metabolic pathways existing in all living …