HLA-C, a gene located within the major histocompatibility complex, has emerged as a
prominent target in biomedical research due to its involvement in various diseases …

Colorectal cancer (CRC) is one of the leading causes of cancer deaths globally. We
implemented a comprehensive literature review regarding CRC genetics studies to offer a …

Aims: This study was designed to determine whether genetic polymorphisms of the killer
immunoglobulin-like receptor (KIR) and human leukocyte antigen class I (HLA-C) genes are …

Background: A set of activating and inhibitory KIRs (aKIR, iKIR) are involved in NK cell
mediated immunity. This study was carried out in order to investigate the KIRs pattern and its …

Breast cancer (BC) progression and metastases have been linked to antitumor immunity
inefficiency and particularly to natural killer (NK) cells. Killer cell immunoglobulin-like …

Background This study attempted to verify the potential of KCNJ14 as a biomarker in
colorectal cancer (CRC). Methods Data on transcriptomics and DNA methylation and the …

Aim To ascertain whether killer cell immunoglobulin-like receptors (KIR) genes
polymorphisms and HLA-I ligands are associated with COVID-19 in Saudi Arabia. Methods …

Background Killer immunoglobulin-like receptors (KIRs) are key molecules used by natural
killer (NK) cells to interact with target cells. These receptors exhibit extensive genotypic …

Colorectal cancer (CRC) is the most common cause of cancer-related mortality globally. It
ranks as the most common cancer among men and the third most prevalent among women …

Colorectal cancer (CRC) can occur anywhere in the colon or rectum and represents the third
most common cancer in the world in both sexes. Natural killer cells (NK) are part of the …