Autophagy as a molecular target for cancer treatment

NM Kocaturk, Y Akkoc, C Kig, O Bayraktar… - European Journal of …, 2019 - Elsevier
Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …

The genus Polygonatum: A review of ethnopharmacology, phytochemistry and pharmacology

P Zhao, C Zhao, X Li, Q Gao, L Huang, P Xiao… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance The genus Polygonatum (Asparagaceae)
comprises 71 species distributed throughout the temperate Northern Hemisphere. The …

Regulation of mammalian autophagy in physiology and pathophysiology

B Ravikumar, S Sarkar, JE Davies… - Physiological …, 2010 - journals.physiology.org
(Macro) autophagy is a bulk degradation process that mediates the clearance of long-lived
proteins and organelles. Autophagy is initiated by double-membraned structures, which …

Recent insights into the mitochondrial role in autophagy and its regulation by oxidative stress

V Roca-Agujetas, C de Dios, L Lestón… - Oxidative medicine …, 2019 - Wiley Online Library
Autophagy is a self‐digestive process that degrades intracellular components, including
damaged organelles, to maintain energy homeostasis and to cope with cellular stress …

Lectins with potential for anti-cancer therapy

T Yau, X Dan, CCW Ng, TB Ng - Molecules, 2015 - mdpi.com
This article reviews lectins of animal and plant origin that induce apoptosis and autophagy of
cancer cells and hence possess the potential of being developed into anticancer drugs …

Safety considerations on food protein-derived bioactive peptides

L Liu, S Li, J Zheng, T Bu, G He, J Wu - Trends in food science & …, 2020 - Elsevier
Background Bioactive peptides derived from food proteins are continuing gain the
momentum as an important constituent of functional food ingredients and nutraceuticals …

An updated review on food‐derived bioactive peptides: Focus on the regulatory requirements, safety, and bioavailability

PJ Patil, M Usman, C Zhang… - … Reviews in Food …, 2022 - Wiley Online Library
Food‐derived bioactive peptides (BAPs) are recently utilized as functional food raw
materials owing to their potential health benefits. Although there is a huge amount of …

[HTML][HTML] β-Hydroxybutyrate induces bovine hepatocyte apoptosis via an ROS-p38 signaling pathway

Y Song, N Li, J Gu, S Fu, Z Peng, C Zhao, Y Zhang… - Journal of Dairy …, 2016 - Elsevier
Abstract β-Hydroxybutyrate (BHB) is an important indicator for metabolic disorders in dairy
cows, such as ketosis and fatty liver. Dairy cows with ketosis display oxidative stress that …

Plant lectins in cancer therapeutics: Targeting apoptosis and autophagy-dependent cell death

SK Bhutia, PK Panda, N Sinha, PP Praharaj… - Pharmacological …, 2019 - Elsevier
Plant lectins are non-immunoglobin in nature and bind to the carbohydrate moiety of the
glycoconjugates without altering any of the recognized glycosyl ligands. Plant lectins have …

Mitochondrial ROS generation for regulation of autophagic pathways in cancer

Z Li, Y Yang, M Ming, B Liu - Biochemical and biophysical research …, 2011 - Elsevier
Mitochondria, the main source of reactive oxygen species (ROS), are required for cell
survival; yet also orchestrate programmed cell death (PCD), referring to apoptosis and …