Mango (Mangifera indica) is one of the most popular fruits in the world. During processing,
the byproducts such as peel, seed and kernel are produced, which are high in bioactive …

Unhealthy dietary patterns-induced obesity and obesity-related complications pose a great
threat to human health all over the world. Accumulating evidence suggests that the …

Chronic inflammation is crucial for the pathological process of tumors due to increasing the
infiltration of cytokines, growth factors, and chemokines to the tumor microenvironment …

Traditional bone tissue engineering (BTE) strategies induce direct bone-like matrix formation
by mimicking the embryological process of intramembranous ossification. However, the …

In order to solve the clinical challenges related to bone grafting, several tissue engineering
(TE) strategies have been proposed to repair critical-sized defects. Generally, the classical …

Diabetic peripheral neuropathy (DPN) is the most common neuropathy in the world, mainly
manifested as bilateral symmetry numbness, pain or paresthesia, with a high rate of …

Schwann cells are the main supportive cells of the peripheral nerves. Schwann cells suffer
inhibition of autophagy under hyperglycemia treatment in diabetic peripheral neuropathy …

Osteoarthritis (OA) is an age‐related degenerative disease with complicated pathology
involving chondrocyte apoptosis and extracellular matrix (ECM) degradation. Previous …

Chondrogenesis involves the recruitment and migration of mesenchymal cells,
mesenchymal condensation, and chondrocyte differentiation and hypertrophy. Multiple …

A wide range of natural products including, flavonoids have been studied for their
therapeutic potential in different diseases. Mangiferin (2-cbd-glucopyranosyl 1, 3, 6, 7 …