Spatiotemporal control of liquid crystal structure and dynamics through activity patterning

R Zhang, SA Redford, PV Ruijgrok, N Kumar… - Nature materials, 2021 - nature.com
Active materials are capable of converting free energy into mechanical work to produce
autonomous motion, and exhibit striking collective dynamics that biology relies on for …

Motility of an autonomous protein-based artificial motor that operates via a burnt-bridge principle

CS Korosec, IN Unksov, P Surendiran… - Nature …, 2024 - nature.com
Inspired by biology, great progress has been made in creating artificial molecular motors.
However, the dream of harnessing proteins–the building blocks selected by nature–to …

[HTML][HTML] Cryo-electron microscopy analysis of myosin at work and at rest

SN McMillan, CA Scarff - Current Opinion in Structural Biology, 2022 - Elsevier
Myosins are a superfamily of ATP-driven actin-dependent molecular motors that are
responsible for diverse functions from muscle contraction to cell division. The resolution …

Machine learning active-nematic hydrodynamics

J Colen, M Han, R Zhang, SA Redford… - Proceedings of the …, 2021 - National Acad Sciences
Hydrodynamic theories effectively describe many-body systems out of equilibrium in terms of
a few macroscopic parameters. However, such parameters are difficult to determine from …

Exploitation of engineered light-switchable myosin XI for nanotechnological applications

A Salhotra, MA Rahman, PV Ruijgrok, CR Meinecke… - ACS …, 2023 - ACS Publications
For certain nanotechnological applications of the contractile proteins actin and myosin, eg.,
in biosensing and network-based biocomputation, it would be desirable to temporarily …

Optogenetic control of apical constriction induces synthetic morphogenesis in mammalian tissues

G Martínez-Ara, N Taberner, M Takayama… - Nature …, 2022 - nature.com
The emerging field of synthetic developmental biology proposes bottom-up approaches to
examine the contribution of each cellular process to complex morphogenesis. However, the …

Comparison of actin-and microtubule-based motility systems for application in functional nanodevices

C Reuther, R Catalano, A Salhotra… - New Journal of …, 2021 - iopscience.iop.org
Over the last 25 years, extensive progress has been made in developing a range of
nanotechnological applications where cytoskeletal filaments and molecular motors are key …

Controlling active turbulence by activity patterns

A Partovifard, J Grawitter, H Stark - Soft Matter, 2024 - pubs.rsc.org
By patterning activity in space, one can control active turbulence. To show this, we use Doi's
hydrodynamic equations of a semidilute solution of active rods. A linear stability analysis …

Discovery of ultrafast myosin, its amino acid sequence, and structural features

T Haraguchi, M Tamanaha, K Suzuki… - Proceedings of the …, 2022 - National Acad Sciences
Cytoplasmic streaming with extremely high velocity (∼ 70 μm s− 1) occurs in cells of the
characean algae (Chara). Because cytoplasmic streaming is caused by myosin XI, it has …

Motor crosslinking augments elasticity in active nematics

SA Redford, J Colen, JL Shivers, S Zemsky, M Molaei… - Soft Matter, 2024 - pubs.rsc.org
In active materials, uncoordinated internal stresses lead to emergent long-range flows. An
understanding of how the behavior of active materials depends on mesoscopic …