Boron agents for neutron capture therapy

K Hu, Z Yang, L Zhang, L Xie, L Wang, H Xu… - Coordination Chemistry …, 2020 - Elsevier
Boron neutron capture therapy (BNCT) is a potential cancer radiotherapeutic modality,
which takes advantage of the neutron capture response that occurs when boron (10 B) is …

Carbaboranes as pharmacophores: properties, synthesis, and application strategies

M Scholz, E Hey-Hawkins - Chemical Reviews, 2011 - ACS Publications
Medicinal chemistry is still clearly dominated by organic chemistry. Most of the marketed
drugs are purely organic molecules. The right-hand neighbors of carbon in the periodic …

Recent progress in fabrication and application of BN nanostructures and BN-based nanohybrids

DV Shtansky, AT Matveev, ES Permyakova, DV Leybo… - Nanomaterials, 2022 - mdpi.com
Due to its unique physical, chemical, and mechanical properties, such as a low specific
density, large specific surface area, excellent thermal stability, oxidation resistance, low …

Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2

P Wongthai, K Hagiwara, Y Miyoshi… - Cancer …, 2015 - Wiley Online Library
The efficacy of boron neutron capture therapy relies on the selective delivery of boron
carriers to malignant cells. p‐Boronophenylalanine (BPA), a boron delivery agent, has been …

On-demand biodegradable boron nitride nanoparticles for treating triple negative breast cancer with boron neutron capture therapy

L Li, J Li, Y Shi, P Du, Z Zhang, T Liu, R Zhang, Z Liu - Acs Nano, 2019 - ACS Publications
Compared with photon-induced binary cancer therapy, such as photothermal therapy (PTT)
and photodynamic therapy (PDT), boron neutron capture therapy (BNCT) emerges as an …

Exosome‐Coated 10B Carbon Dots for Precise Boron Neutron Capture Therapy in a Mouse Model of Glioma In Situ

J Li, J Kong, S Ma, J Li, M Mao, K Chen… - Advanced Functional …, 2021 - Wiley Online Library
Novel boron‐containing carbon dots (BCDs) are designed and prepared for boron neutron
capture therapy (BNCT) with superior water solubility and excellent optical property for …

The development of boron analysis and imaging in boron neutron capture therapy (BNCT)

Q Dai, QY Yang, X Bao, J Chen, M Han… - Molecular …, 2022 - ACS Publications
Boron neutron capture therapy (BNCT) is a selective biological targeted nuclide technique
for cancer therapy. It has the following attractive features: good targeting, high effectiveness …

In Vivo Evaluation of Multifunctional Gold Nanorods for Boron Neutron Capture and Photothermal Therapies

KR Pulagam, M Henriksen-Lacey… - … Applied Materials & …, 2021 - ACS Publications
The incidence and mortality of cancer demand more innovative approaches and
combination therapies to increase treatment efficacy and decrease off-target side effects. We …

Advancements in tumor targeting strategies for boron neutron capture therapy

MJ Luderer, P De La Puente, AK Azab - Pharmaceutical research, 2015 - Springer
Boron neutron capture therapy (BNCT) is a promising cancer therapy modality that utilizes
the nuclear capture reaction of epithermal neutrons by boron-10 resulting in a localized …

Carborane bearing pullulan nanogel-boron oxide nanoparticle hybrid for boron neutron capture therapy

R Kawasaki, H Hirano, K Yamana, H Isozaki… - … , Biology and Medicine, 2023 - Elsevier
Boron neutron capture therapy shows is a promising approach to cancer therapy, but the
delivery of effective boron agents is challenging. To address the requirements for efficient …