Spliceosomal introns, which have been found in most eukaryotic genes, are non-coding
sequences excised from pre-mRNAs by a special complex called spliceosome during …

Simple Summary CRISPR/Cas9 enables efficient mutagenesis and generation of various
knockout and knockin alleles in many species including zebrafish. However, the application …

Genomic GC content can vary locally, and GC‐rich regions are usually associated with
increased DNA thermostability in thermophilic prokaryotes and warm‐blooded eukaryotes …

Background Temperature adaptation of biological molecules is fundamental in evolutionary
studies but remains unsolved. Fishes living in cold water are adapted to low temperatures …

Background The DNA base composition is well known to be highly variable among
organisms. Bio-physic studies on the effect of the GC increments on the DNA structure have …

Random mutations increase genetic variety and natural selection enhances adaption over
generations. Codon usage biases (CUB) provide clues about the genome adaptation …

The impact of spliceosomal introns on genome and organismal evolution remains puzzling.
Here, we investigated the correlative associations among genome-wide features of introns …

Environmental interactions and the effects of such interactions on the evolution of genome
attributes is an intriguing area of ongoing research. Several earlier studies have delved into …

Для большинства эукариотических генов свойственны сплайсосомные интроны-
некодирующие последовательности, которые вырезаются из пре-мРНК генов с …

In zebrafish, RNA-guided endonucleases such as Cas9 have enabled straightforward gene
knockout and the construction of reporter lines or conditional alleles via targeted knockin …