Monocyte activation in immunopathology: cellular test for development of diagnostics and therapy

EA Ivanova, AN Orekhov - Journal of immunology research, 2016 - Wiley Online Library
Several highly prevalent human diseases are associated with immunopathology. Alterations
in the immune system are found in such life‐threatening disorders as cancer and …

Peripheral blood cells, a transcriptomic tool in nutrigenomic and obesity studies: current state of the art

B Reynés, T Priego, M Cifre, P Oliver… - … reviews in food science …, 2018 - Wiley Online Library
Gene expression profile of peripheral blood cells (PBC) is able to reflect useful aspects of
the whole body metabolic status. Therefore, and favored by the huge development of “omic” …

Use of human PBMC to analyse the impact of obesity on lipid metabolism and metabolic status: a proof-of-concept pilot study

A Costa, B Reynés, J Konieczna, M Martín, M Fiol… - Scientific reports, 2021 - nature.com
Peripheral blood mononuclear cells (PBMC) are widely used as a biomarker source in
nutrition/obesity studies because they reflect gene expression profiles of internal tissues. In …

Cognitive impairment in metabolically-obese, normal-weight rats: identification of early biomarkers in peripheral blood mononuclear cells

M Cifre, A Palou, P Oliver - Molecular neurodegeneration, 2018 - Springer
Background Metabolically-obese, normal-weight (MONW) individuals are not obese in terms
of weight and height but have a number of obesity-related features (eg greater visceral …

A genetic score of predisposition to low-grade inflammation associated with obesity may contribute to discern population at risk for metabolic syndrome

S Galmés, M Cifre, A Palou, P Oliver, F Serra - Nutrients, 2019 - mdpi.com
Omega-3 rich diets have been shown to improve inflammatory status. However, in an ex vivo
system of human blood cells, the efficacy of eicosapentaenoic acid (EPA) and …

Identification of Mest/Peg1 gene expression as a predictive biomarker of adipose tissue expansion sensitive to dietary anti-obesity interventions

A Voigt, J Ribot, AG Sabater, A Palou, ML Bonet… - Genes & nutrition, 2015 - Springer
Food components with anti-obesity properties are commonly evaluated using mouse models
of diet-induced obesity. The ability of these components to reduce or prevent white adipose …

Peripheral blood mononuclear cells antioxidant adaptations to regular physical activity in elderly people

C Busquets-Cortés, X Capó, MM Bibiloni, M Martorell… - Nutrients, 2018 - mdpi.com
Regular physical activity prescription is a key point for healthy aging and chronic disease
management and prevention. Our aim was to evaluate the antioxidant defense system and …

Gene expression modulation of lipid and central energetic metabolism related genes by high-fat diet intake in the main homeostatic tissues

B Reynés, M Palou, A Palou - Food & function, 2017 - pubs.rsc.org
It is generally assumed that high-fat (HF) diets induce characteristic gene expression
regulation, which may cause metabolic alterations associated with an increased risk of …

Efficacy of different modalities and frequencies of physical exercise on glucose control in people with prediabetes (GLYCEX randomised trial)

AM Galmes-Panades, M Bennasar-Veny, P Oliver… - Metabolites, 2022 - mdpi.com
To assess the efficacy of different modalities and frequencies of physical exercise on
glycaemic control in adults with prediabetes. A two-phase, parallel, randomised, controlled …

Cpt1a gene expression in peripheral blood mononuclear cells as an early biomarker of diet-related metabolic alterations

R Díaz-Rúa, A Palou, P Oliver - Food & nutrition research, 2016 - Taylor & Francis
Background Research on biomarkers that provide early information about the development
of future metabolic alterations is an emerging discipline. Gene expression analysis in …