A practical guide for induction of type-2 diabetes in rat: Incorporating a high-fat diet and streptozotocin

S Gheibi, K Kashfi, A Ghasemi - Biomedicine & pharmacotherapy, 2017 - Elsevier
Prevalence of diabetes, a serious public health problem is rapidly increasing worldwide.
Type-2 diabetes is the common form of diabetes characterized by insulin resistance and …

NO donors as the wonder molecules with therapeutic potential: Recent trends and future perspectives

GR Navale, S Singh, K Ghosh - Coordination Chemistry Reviews, 2023 - Elsevier
Nitric oxide (NO), an endogenous, free radical, highly unstable, diatomic gaseous molecule,
plays crucial roles in several physiological and pathological processes. It has attracted …

metaGEM: reconstruction of genome scale metabolic models directly from metagenomes

F Zorrilla, F Buric, KR Patil… - Nucleic Acids Research, 2021 - academic.oup.com
Metagenomic analyses of microbial communities have revealed a large degree of
interspecies and intraspecies genetic diversity through the reconstruction of metagenome …

Interplay among the oral microbiome, oral cavity conditions, the host immune response, diabetes mellitus, and its associated-risk factors—An overview

TC Negrini, IZ Carlos, C Duque, KS Caiaffa… - Frontiers in oral …, 2021 - frontiersin.org
This comprehensive review of the literature aimed to investigate the interplay between the
oral microbiome, oral cavity conditions, and host immune response in Diabetes mellitus …

Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension

S Gheibi, S Jeddi, K Kashfi, A Ghasemi - Biochemical pharmacology, 2018 - Elsevier
Nitric oxide (NO) and hydrogen sulfide (H 2 S) are two gasotransmitters that are produced in
the vasculature and contribute to the regulation of vascular tone. NO and H 2 S are …

Glycosides and flavonoids from the extract of Pueraria thomsonii Benth leaf alleviate type 2 diabetes in high-fat diet plus streptozotocin-induced mice by modulating …

SS Zhang, NN Zhang, S Guo, SJ Liu, YF Hou, S Li… - Food & Function, 2022 - pubs.rsc.org
Twenty glycoside derivatives and nine flavonoids from the leaves of Pueraria (P. thomsonii)
were isolated by column chromatography and characterized by nuclear magnetic resonance …

From nitrate to NO: potential effects of nitrate-reducing bacteria on systemic health and disease

H Liu, Y Huang, M Huang, M Wang, Y Ming… - European Journal of …, 2023 - Springer
Current research has described improving multisystem disease and organ function through
dietary nitrate (DN) supplementation. They have provided some evidence that these floras …

AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis

I Cordero-Herrera, M Kozyra, Z Zhuge… - Proceedings of the …, 2019 - National Acad Sciences
Advanced age and unhealthy dietary habits contribute to the increasing incidence of obesity
and type 2 diabetes. These metabolic disorders, which are often accompanied by oxidative …

Nitrate reduction capacity of the oral microbiota is impaired in periodontitis: potential implications for systemic nitric oxide availability

BT Rosier, W Johnston, M Carda-Diéguez… - International Journal of …, 2024 - nature.com
The reduction of nitrate to nitrite by the oral microbiota has been proposed to be important
for oral health and results in nitric oxide formation that can improve cardiometabolic …

Interactions of preservatives in meat processing: Formation of carcinogenic compounds, analytical methods, and inhibitory agents

L Molognoni, H Daguer, GE Motta, TC Merlo… - Food research …, 2019 - Elsevier
Meat products are important for balanced diets because of their nutritional richness.
However, noxious compounds may be formed by interactions among reactants and specific …