Synthesis, reactions and application of chalcones: A systematic review

MA Shalaby, SA Rizk, AM Fahim - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
Chalcones are a group of naturally occurring compounds that have biological effects that
include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone …

A review on synthetic chalcone derivatives as tubulin polymerisation inhibitors

W Liu, M He, Y Li, Z Peng, G Wang - Journal of enzyme inhibition …, 2022 - Taylor & Francis
Microtubules play an important role in the process of cell mitosis and can form a spindle in
the mitotic prophase of the cell, which can pull chromosomes to the ends of the cell and then …

Bischalcone derivatives with fluorine and methoxy functional groups: Synthesis, molecular docking, and biological evaluation as potential anticancer agents

S Ozcan, DA Anil, GY Ozkat, F Sanli, OF Karatas… - Journal of Molecular …, 2025 - Elsevier
The present study employed the Claisen-Schmidt condensation reaction to synthesize a
series of bischalcones featuring fluorine atoms positioned at different positions in the B rings …

Organohalogen chalcones: design, synthesis, ADMET prediction, molecular dynamics study and inhibition effect on acetylcholinesterase and carbonic anhydrase

BO Aydin, DA Anil, Y Demir, MA Alagoz - Molecular Diversity, 2024 - Springer
In an effort to discover potential acetylcholinesterase (AChE) and carbonic anhydrase (CA)
inhibitors, a novel series of organohalogen chalcone derivatives (12–20, 23–30) was …

Investigation of Some Metabolic Enzyme Inhibition Properties of Novel Chalcone‐Cu Complexes

R Ebiri, M Turgut, D Aktas Anil, Y Demir… - …, 2024 - Wiley Online Library
Abstract Fourteen novel Chalcone‐Cu complexes were effectively synthesized in this work.
The newly synthesized Chalcone‐Cu complexes were assessed for their effects on human …

Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives

S Burmaoglu, A Gobek, DA Anil… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Pathological angiogenesis plays a critical role in tumorigenesis and tumor progression, and
anti-angiogenesis therapies have evinced promising antitumor effects in solid tumors …