Candida albicans is a common fungus of the human microbiota. While generally a harmless commensal in healthy individuals, several factors can lead to its overgrowth and cause a …
R Alonso-Roman, A Last, MH Mirhakkak… - Nature …, 2022 - nature.com
Intestinal microbiota dysbiosis can initiate overgrowth of commensal Candida species–a major predisposing factor for disseminated candidiasis. Commensal bacteria such as …
Pathogenic fungi have become a leading cause of human mortality due to the increasing frequency of fungal infections in immunocompromised populations and the limited …
Biofilms are a principal form of microbial growth and are critical to development of clinical infection. They are responsible for a broad spectrum of microbial infections in the human …
WLJ Chaffin - Microbiology and molecular biology reviews, 2008 - Am Soc Microbiol
The Candida albicans cell wall maintains the structural integrity of the organism in addtion to providing a physical contact interface with the environment. The major components of the …
M Whiteway, C Bachewich - Annu. Rev. Microbiol., 2007 - annualreviews.org
Candida albicans is termed a dimorphic fungus because it proliferates in either a yeast form or a hyphal form. The switch between these forms is the result of a complex interplay of …
M Polke, B Hube, ID Jacobsen - Advances in Applied Microbiology, 2015 - Elsevier
Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis, and Candida parapsilosis, are successful colonizers of a human host. Under certain …
DK Morales, N Grahl, C Okegbe, LEP Dietrich… - MBio, 2013 - Am Soc Microbiol
Candida albicans has developmental programs that govern transitions between yeast and filamentous morphologies and between unattached and biofilm lifestyles. Here, we report …
C Puerner, S Vellanki, JL Strauch… - Annual Review of …, 2023 - annualreviews.org
Fungal-mediated disease progression and antifungal drug efficacy are significantly impacted by the dynamic infection microenvironment. At the site of infection, oxygen often …