Research review: polygenic methods and their application to psychiatric traits

NR Wray, SH Lee, D Mehta… - Journal of child …, 2014 - Wiley Online Library
Background Despite evidence from twin and family studies for an important contribution of
genetic factors to both childhood and adult onset psychiatric disorders, identifying robustly …

Biomarkers in the diagnosis of ADHD–promising directions

SV Faraone, C Bonvicini, C Scassellati - Current psychiatry reports, 2014 - Springer
The etiology and pathogenesis of attention-deficit/hyperactivity disorder (ADHD) are unclear
and a more valid diagnosis would certainly be welcomed. Starting from the literature, we …

The revolution of personalized psychiatry: will technology make it happen sooner?

G Perna, M Grassi, D Caldirola… - Psychological medicine, 2018 - cambridge.org
Personalized medicine (PM) aims to establish a new approach in clinical decision-making,
based upon a patient's individual profile in order to tailor treatment to each patient's …

[图书][B] Moral injury and soldiers in conflict: Political practices and public perceptions

T Molendijk - 2021 - taylorfrancis.com
This book advances an interdisciplinary understanding of moral injury by analyzing the
stories of military veterans of combat and peace missions. In the past decade, the concept of …

Applications of blood-based protein biomarker strategies in the study of psychiatric disorders

MK Chan, MG Gottschalk, F Haenisch, J Tomasik… - Progress in …, 2014 - Elsevier
Major psychiatric disorders such as schizophrenia, major depressive and bipolar disorders
are severe, chronic and debilitating, and are associated with high disease burden and …

A pilot proteomic analysis of salivary biomarkers in autism spectrum disorder

AG Ngounou Wetie, KL Wormwood, S Russell… - Autism …, 2015 - Wiley Online Library
Autism spectrum disorder (ASD) prevalence is increasing, with current estimates at 1/68–
1/50 individuals diagnosed with an ASD. Diagnosis is based on behavioral assessments …

Identification of posttranslational modifications (PTMs) of proteins by mass spectrometry

R Aslebagh, KL Wormwood… - Advancements of mass …, 2019 - Springer
There are only 30,000 human genes, which, according to the central dogma from biology, it
means that there should be 30,000 mRNA and 30,000 proteins. However, there are at least …

Evaluation of serum Neuron-specific enolase, S100B, myelin basic protein and glial fibrilliary acidic protein as brain specific proteins in children with autism spectrum …

E Esnafoglu, SN Ayyıldız, S Cırrık, EY Erturk… - International Journal of …, 2017 - Elsevier
Objective Brain specific-proteins are not found in other tissues and measurement non-
invasively in the blood may identify structurally and functionally damaged brain regions and …

Development and validation of a simple, rapid and sensitive LC-MS/MS method for the measurement of urinary neurotransmitters and their metabolites

J Yan, U Kuzhiumparambil, S Bandodkar… - Analytical and …, 2017 - Springer
Neurotransmitters play crucial roles in physiological functions and their imbalances have
demonstrated association in the pathology of several diseases. The measurement of …

Translational bioinformatics and data science for biomarker discovery in mental health: an analytical review

K Bhuvaneshwar, Y Gusev - Briefings in Bioinformatics, 2024 - academic.oup.com
Translational bioinformatics and data science play a crucial role in biomarker discovery as it
enables translational research and helps to bridge the gap between the bench research and …