Infections are a major threat to human reproductive health, and infections in pregnancy can
cause prematurity or stillbirth, or can be vertically transmitted to the fetus leading to …

Pregnancy poses an immunological challenge because a genetically distinct (nonself) fetus
must be supported within the pregnant female for the required gestational period …

Positive-sense single-stranded RNA (+ ssRNA) viruses comprise many (re-) emerging
human pathogens that pose a public health problem. Our innate immune system and, in …

Zika virus (ZIKV) is an emerging virus from the Flaviviridae family that is transmitted to
humans by mosquito vectors and represents an important health problem. Infections in …

Why certain viruses cross the physical barrier of the human placenta but others do not is
incompletely understood. Over the past 20 years, we have gained deeper knowledge of …

Although Zika virus (ZIKV)-induced congenital disease occurs more frequently during early
stages of pregnancy, its basis remains undefined. Using established type I interferon (IFN) …

The nasal mucosa constitutes the primary entry site for respiratory viruses, including severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While the imbalanced innate …

Hepatitis E virus (HEV) infection, particularly HEV genotype 1 (HEV-1), can result in
fulminant hepatic failure and severe placental diseases, but mechanisms underlying …

Zika virus (ZIKV) became a public health emergency of global concern in 2015 due to its
rapid expansion from French Polynesia to Brazil, spreading quickly throughout the …

Nipah virus causes highly lethal disease, with case-fatality rates ranging from 40% to 100%
in recognised outbreaks. No treatments or licensed vaccines are currently available for the …