[HTML][HTML] A review of the recent development in the synthesis and biological evaluations of pyrazole derivatives

O Ebenezer, M Shapi, JA Tuszynski - Biomedicines, 2022 - mdpi.com
Pyrazoles are five-membered heterocyclic compounds that contain nitrogen. They are an
important class of compounds for drug development; thus, they have attracted much …

Thiazole-based analogs as potential antibacterial agents against methicillin-resistant Staphylococcus aureus (MRSA) and their SAR elucidation

J Guo, Z Xie, W Ruan, Q Tang, D Qiao, W Zhu - European Journal of …, 2023 - Elsevier
In recent years, the overuse of antibiotics has resulted in the emergence of antibiotic
resistance, which is a serious global health problem. Methicillin-resistant Staphylococcus …

Antibacterial pyrazoles: Tackling resistant bacteria

MA Alam - Future Medicinal Chemistry, 2022 - Taylor & Francis
Bacterial resistance to antibiotics threatens our progress in healthcare, modern medicine,
food production and ultimately life expectancy. Antibiotic resistance is a global concern …

Synthesis, biological screening and in silico studies of new N-phenyl-4-(1, 3-diaryl-1H-pyrazol-4-yl) thiazol-2-amine derivatives as potential antifungal and …

Y Nandurkar, MR Bhoye, D Maliwal… - European Journal of …, 2023 - Elsevier
A new series of N-aryl-4-(1, 3-diaryl-1H-pyrazol-4-yl) thiazol-2-amine,(8a-x) have been
synthesized by a cyclo-condensation reaction of 2-bromo-1-(1, 3-diphenyl-1H-pyrazol-4-yl) …

Synthesis and Biological Screening of New 2-(5-Aryl-1-phenyl-1H-pyrazol-3-yl)-4-aryl Thiazole Derivatives as Potential Antimicrobial Agents

Y Nandurkar, A Shinde, MR Bhoye, S Jagadale… - ACS …, 2023 - ACS Publications
A new series of 2-(5-aryl-1-phenyl-1 H-pyrazol-3-yl)-4-aryl thiazoles (10a–ab) have been
synthesized by a cyclocondensation reaction of 5-aryl-1-phenyl-1 H-pyrazole-3 …

Antimicrobial evaluation of new pyrazoles, indazoles and pyrazolines prepared in continuous flow mode

A Burke, M Di Filippo, S Spiccio, AM Schito… - International Journal of …, 2023 - mdpi.com
Multi-drug resistant bacterial strains (MDR) have become an increasing challenge to our
health system, resulting in multiple classical antibiotics being clinically inactive today. As the …

A new insight into the synthesis and biological activities of pyrazole based derivatives

S Mor, M Khatri, R Punia, S Nagoria… - Mini-Reviews in …, 2022 - ingentaconnect.com
This review aims to collate literature work reported by researchers (from 1994 to 2021) to
provide an overview of the available methodologies for the synthesis and diverse …

Synthesis, Antimicrobial, and Anticancer Activities of Novel Nitrofuran Derivatives

MS Mohamed, KM Elamin, R Alenazy… - Journal of …, 2023 - Wiley Online Library
Keeping in view the varying therapeutic attributes of 5‐nitrofuran and isatin derivatives,
novel 5‐nitrofuran‒isatin molecular hybrids (2, 5–7) were synthesized by standard …

Antibacterial and Antifungal Pyrazoles Based on Different Construction Strategies

MU Rehman, F He, X Shu, J Guo, Z Liu, S Cao… - European Journal of …, 2024 - Elsevier
The growing prevalence of microbial infections, and antimicrobial resistance (AMR)
stemming from the overuse and misuse of antibiotics, call for novel therapeutic agents …

One-Pot Cascade Access to Ru(II)-Catalyzed Regioselective C(sp2)-H Activation/Alkenylation of Chromeno[4,3-c]pyrazol-4-ones and Their Emission Solvatochromic …

D Singla, K Paul - The Journal of Organic Chemistry, 2022 - ACS Publications
Herein, one-pot cascade synthesis of chromeno [4, 3-c] pyrazol-4-ones and their Ru (II)-
catalyzed regioselective ortho-alkenylation using imine as a weak directing group are done …