Most higher animals require sight for survival, yet even minor distortions of the visual axis
can cause blindness. For this reason, intraocular inflammation is incompatible with good …

Immune-mediated inflammation and allograft rejection are greatly reduced in certain organs,
a phenomenon called'immune privilege'. Immune privilege is well developed in three …

Apoptosis is crucially important in mediating immune privilege of the fetus during pregnancy.
We investigated the expression and in vitro apoptotic activity of two physiologically relevant …

It has recently been recognized that pathology of age-associated degenerative eye diseases
such as adult macular degeneration (AMD), glaucoma and diabetic retinopathy, have strong …

Since the invading trophoblast represents a semi‐allograft, it should be rejected by the
mother. It has, therefore, been postulated that during normal pregnancy the trophoblast …

Background Glaucoma is a complex, multifactorial disease where apoptosis, microglia
activation, and inflammation have been linked to the death of retinal ganglion cells (RGCs) …

Uveitis is a sight-threatening disease caused by autoimmune or infection-related immune
responses. Studies in experimental autoimmune uveitis and in human diseases imply that …

The local immune privilege of the fetus is created by the placenta. Fas ligand (FasL)
expression in trophoblast has been implied as one of the mechanisms of fetal tolerance …

The first known hormonal signal of the conceptus during implantation is human chorionic
gonadotropin (hCG). Interestingly, increased apoptosis in human endometrium coincides …

Endophthalmitis is an infection of the posterior segment of the eye that frequently results in
loss of vision. This devastating result occurs despite prompt and often aggressive …