Objective Identifying risk factors for Achilles Tendon Rupture (ATR) is one of the first
necessary steps for its prevention. This systematic review aimed to update the systematic …

Tendon aging is associated with an increasing prevalence of tendon injuries and/or chronic
tendon diseases, such as tendinopathy, which affects approximately 25% of the adult …

Appropriate macrophage response to an implanted biomaterial is crucial for successful
tissue healing outcomes. In this work we investigated how intrinsic topological cues from …

As Western diets continue to include an ever-increasing amount of sugar, there has been a
rise in obesity and type 2 diabetes. To avoid metabolic diseases, the body must maintain …

Tenomodulin (Tnmd) is the best-known mature marker for tendon and ligament lineage
cells. It is important for tendon maturation, running performance and has key implications for …

Background Tendinopathy is a common motor system disease that leads to pain and
reduced function. Despite its prevalence, our mechanistic understanding is incomplete …

The SOX family plays a vital role in determining the fate of cells and has garnered attention
in the fields of cancer research and regenerative medicine. It also shows promise in the …

Tendon and ligament injuries are the most common musculoskeletal injuries, which not only
impact the quality of life but result in a massive economic burden. Surgical interventions for …

Abstract Purpose of Review This review seeks to provide an overview of the role of
inflammation and metabolism in tendon cell function, tendinopathy, and tendon healing. We …

Achilles tendon rupture is a common debilitating medical condition. The healing process is
slow and can be affected by heterotopic ossification (HO), which occurs when pathologic …