Benzodiazepines (BZDs) are among one of the most widely prescribed drug classes in the
United States. BZDs are a class of psychoactive drugs known for their depressant effect on …

Abstract The American College of Physicians (ACP) recently identified cognitive behavioral
therapy for insomnia (CBT-I) as the first-line treatment for insomnia. Although CBT-I …

Background Most patients with irritable bowel syndrome (IBS) are managed in primary care.
When first-line therapies for IBS are ineffective, the UK National Institute for Health and Care …

Importance Although concern exists regarding the rate of benzodiazepine use, especially
long-term use by older adults, little information is available concerning patterns of …

Insomnia, the most prevalent sleep disorder worldwide, confers marked risks for both
physical and mental health. Furthermore, insomnia is associated with considerable direct …

Background Sleep hygiene education (SHE) is commonly used as a treatment of insomnia
in general practice. Whether SHE or cognitive-behavioural therapy for insomnia (CBT-I), a …

Background Insomnia is prevalent and distressing but access to the first-line treatment,
cognitive behavioural therapy (CBT), is extremely limited. We aimed to assess the clinical …

Introduction Although many clinical guidelines caution against the combined use of opioids
and benzodiazepines, overdose deaths and emergency department visits involving the co …

Background Insomnia disorder is a subjective condition of unsatisfactory sleep (eg sleep
onset, maintenance, early waking, impairment of daytime functioning). Insomnia disorder …

Background Long-term sedative use is prevalent and associated with significant morbidity,
including adverse events such as falls, cognitive impairment, and sedation. The …