Inflammasomes are intracellular complexes involved in the innate immunity that convert
proIL‐1β and proIL‐18 to mature forms and initiate pyroptosis via cleaving procaspase‐1 …

Abstract Background The cJun-N-terminal-kinase (JNK) plays a central role in the cell stress
response, with outcomes ranging from cell death to cell proliferation and survival, depending …

The PI3K/Akt pathway plays a crucial role in the survival, proliferation, and migration of
macrophages, which may impact the development of atherosclerosis. Changes in Akt …

Macrophage apoptosis and the ability of macrophages to clean up dead cells, a process
called efferocytosis, are crucial determinants of atherosclerosis lesion progression and …

Metaflammation, an atypical, metabolically induced, chronic low-grade inflammation, plays
an important role in the development of obesity, diabetes, and atherosclerosis. An important …

Atherosclerosis is characterized by lipid accumulation and chronic inflammation of the
arterial wall, and its main complications—myocardial infarction and ischemic stroke …

The endoplasmic reticulum (ER) is an important organelle that regulates several
fundamental cellular processes, and ER dysfunction has implications for many intracellular …

The walking dead: macrophage inflammation and death in ather... : Current Opinion in
Lipidology The walking dead: macrophage inflammation and death in atherosclerosis : Current …

Atherosclerosis (AS) is the main pathological basis of cardiovascular diseases, which is
mainly characterized by lipid deposition and inflammatory response. Macrophages (MΦ), as …

Endoplasmic reticulum (ER) stress is closely associated with atherosclerosis and related
cardiovascular diseases (CVDs). It occurs due to various pathological factors that interfere …