One proposed mechanism for acute and chronic hepatic encephalopathy (HE) is a
disturbance in cerebral energy metabolism. It also reviews the current status of this …

Abstract Carnitine (β-hydroxy-γ-N-trimethylaminobutyric acid) is required for transport of long-
chain fatty acids into the inner mitochondrial compartment for β-oxidation. Widely distributed …

AIM: To evaluate the influence of L-carnitine on mental conditions and ammonia effects on
patients with hepatic encephalopathy (HE). METHODS: One hundred and fifty patients (10 …

Background Hyperammonemia is a rare, often fatal complication after transplantation. The
etiology is unknown, but recognition and rapid treatment may help to improve the survival of …

Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder.
Behavioural, cognitive and memory dysfunctions are characteristic symptoms of AD. The …

Diet is one of the mainstays of the treatment of patients with urea cycle disorders. The
protein intake should be adjusted to take account of the inborn error and its severity and the …

Abstract l‐carnitine administration prevents the neurological symptoms of acute ammonia
toxicity. To further evaluate its efficacy in the prevention of hepatic encephalopathy in …

Amyotrophic lateral sclerosis (ALS) is a fatal disease caused by progressive degeneration of
motor neurons in the spinal cord and motor cortex. Although the etiology of ALS remains …

Hepatic encephalopathy (HE) is one of the major complications of cirrhosis. Experimental
and clinical findings observed in liver, muscle and brain have provided new insights into the …

Sparse-fur (spf) mutant mice with X-linked ornithine transcarbamylase (OTC) deficiency
were examined for hyperammonemia and its effect on energy metabolism. We compared the …