Animal models of chemotherapy-induced cognitive decline in preclinical drug development

J John, M Kinra, J Mudgal, GL Viswanatha… - …, 2021 - Springer
Rationale Chemotherapy-induced cognitive impairment (CICI), chemobrain, and chemofog
are the common terms for mental dysfunction in a cancer patient/survivor under the influence …

Mammary glands of women, female dogs and female rats: similarities and differences to be considered in breast cancer research

T Ferreira, A Gama, F Seixas, AI Faustino-Rocha… - Veterinary …, 2023 - mdpi.com
Simple Summary Breast cancer research is frequently performed using a variety of models,
including animal models, in an attempt to provide information that can be translated into …

Antioxidant and Antiproliferation Activities of Lemon Verbena (Aloysia citrodora): An In Vitro and In Vivo Study

HM Rashid, AI Mahmod, FU Afifi, WH Talib - Plants, 2022 - mdpi.com
Aloysia citrodora (Verbenaceae) is traditionally used to treat various diseases, including
bronchitis, insomnia, anxiety, digestive, and heart problems. In this study, this plant's …

Chemical Evaluation, In Vitro and In Vivo Anticancer Activity of Lavandula angustifolia Grown in Jordan

NH Aboalhaija, H Syaj, F Afifi, S Sunoqrot, E Al-Shalabi… - Molecules, 2022 - mdpi.com
Lavandula angustifolia is the most widely cultivated Lavandula species for medicinal use. In
this study, chemical and biological evaluation of L. angustifolia aqueous, methanol (MeOH) …

Prognostic factors in MNU and DMBA-induced mammary tumors in female rats

A Alvarado, AC Lopes, AI Faustino-Rocha… - … -Research and Practice, 2017 - Elsevier
Chemically-induced mammary tumors in rats by the carcinogens 1-methyl-1-nitrosourea-
(MNU) and 7, 12-dimethylbenz [a] anthracene (DMBA) are the most widely used models for …

Modelling human prostate cancer: Rat models

E Nascimento-Gonçalves, AI Faustino-Rocha, F Seixas… - Life sciences, 2018 - Elsevier
Prostate cancer is the second most common cancer in men, affecting approximately 1.1
million men worldwide. In this way, the study of prostate cancer biopathology and the study …

Chemical carcinogenesis models of cancer: back to the future

MQ McCreery, A Balmain - Annual Review of Cancer Biology, 2017 - annualreviews.org
Over a century has elapsed since the first demonstration that exposure to chemicals in coal
tar can cause cancer in animals. These observations provided an essential causal …

Protective effects of antioxidant chlorophyllin in chemically induced breast cancer model in vivo

M Ozcan, D Aydemir, M Bacanlı, HG Anlar… - Biological trace element …, 2021 - Springer
Glutathione-related enzymes belong to the protection mechanism of the cells against
harmful oxidative damage and chemicals. Glutathione S-transferase (GST) is frequently over …

Induced mammary cancer in rat models: pathogenesis, genetics, and relevance to female breast cancer

JL Miller, AP Bartlett, RM Harman, PD Majhi… - Journal of Mammary …, 2022 - Springer
Mammary cancer, or breast cancer in women, is a polygenic disease with a complex
etiopathogenesis. While much remains elusive regarding its origin, it is well established that …

A step forward in breast cancer research: From a natural-like experimental model to a preliminary photothermal approach

E Costa, T Ferreira-Gonçalves, M Cardoso… - International Journal of …, 2020 - mdpi.com
Breast cancer is one of the most frequently diagnosed malignancies and common causes of
cancer death in women. Recent studies suggest that environmental exposures to certain …