Ebola virus disease

D Malvy, AK McElroy, H de Clerck, S Günther… - The Lancet, 2019 - thelancet.com
Ebolaviruses are pathogenic agents associated with a severe, potentially fatal, systemic
disease in man and great apes. Four species of ebolaviruses have been identified in west or …

[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat

M Rojas, DM Monsalve, Y Pacheco… - Journal of …, 2020 - Elsevier
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …

Metagenomic surveillance uncovers diverse and novel viral taxa in febrile patients from Nigeria

JU Oguzie, BA Petros, PE Oluniyi, SB Mehta… - Nature …, 2023 - nature.com
Effective infectious disease surveillance in high-risk regions is critical for clinical care and
pandemic preemption; however, few clinical diagnostics are available for the wide range of …

Post-exposure treatments for Ebola and Marburg virus infections

RW Cross, CE Mire, H Feldmann… - Nature Reviews Drug …, 2018 - nature.com
The filoviruses—Ebola virus and Marburg virus—cause lethal haemorrhagic fever in
humans and non-human primates (NHPs). Filoviruses present a global health threat both as …

Pretest symptom duration and cycle threshold values for severe acute respiratory syndrome coronavirus 2 reverse-transcription polymerase chain reaction predict …

EH Miller, J Zucker, D Castor… - Open Forum …, 2021 - academic.oup.com
Background The relationship between severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) viral load and patient symptom duration in both in-and outpatients, and the …

Machine-learning prognostic models from the 2014–16 Ebola outbreak: data-harmonization challenges, validation strategies, and mHealth applications

A Colubri, MA Hartley, M Siakor, V Wolfman… - …, 2019 - thelancet.com
Background Ebola virus disease (EVD) plagues low-resource and difficult-to-access
settings. Machine learning prognostic models and mHealth tools could improve the …

Ebola hemorrhagic shock syndrome-on-a-chip

A Junaid, H Tang, A van Reeuwijk, Y Abouleila… - IScience, 2020 - cell.com
Ebola virus, for which we lack effective countermeasures, causes hemorrhagic fever in
humans, with significant case fatality rates. Lack of experimental human models for Ebola …

Structure based virtual screening of the Ebola virus trimeric glycoprotein using consensus scoring

AT Onawole, TU Kolapo, KO Sulaiman… - … Biology and Chemistry, 2018 - Elsevier
Ebola virus (EBOV) causes zoonotic viral infection with a potential risk of global spread and
a highly fatal effect on humans. Till date, no drug has gotten market approval for the …

The sweet detection of rolling circle amplification: Glucose-based electrochemical genosensor for the detection of viral nucleic acid

S Ciftci, R Cánovas, F Neumann, T Paulraj… - Biosensors and …, 2020 - Elsevier
Herein, an isothermal padlock probe-based assay for the simple and portable detection of
pathogens coupled with a glucose oxidase (GOx)-based electrochemical readout is …

Constructing, validating, and updating machine learning models to predict survival in children with Ebola virus disease

AE Genisca, K Butler, M Gainey, TC Chu… - PLoS Neglected …, 2022 - journals.plos.org
Background Ebola Virus Disease (EVD) causes high case fatality rates (CFRs) in young
children, yet there are limited data focusing on predicting mortality in pediatric patients. Here …