The roles of sex hormones in the course of atopic dermatitis

N Kanda, T Hoashi, H Saeki - International journal of molecular sciences, 2019 - mdpi.com
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by T helper 2 cell
(Th2)-shifted abnormal immunity, skin barrier impairment, and pruritus. The prevalence of …

The role of virus infection in deregulating the cytokine response to secondary bacterial infection

D Mehta, C Petes, K Gee, S Basta - Journal of Interferon & Cytokine …, 2015 - liebertpub.com
Proinflammatory cytokines are produced by macrophages and dendritic cells (DCs) after
infection to stimulate T helper (Th) cells, linking innate and adaptive immunity. Virus …

Expansion of CD25-Negative Forkhead Box P3-Positive T Cells during HIV and Mycobacterium tuberculosis Infection

MT Angerami, GV Suarez, MB Vecchione… - Frontiers in …, 2017 - frontiersin.org
Tuberculosis (TB) and HIV alter the immune system, and coinfected (HIV-TB) individuals
usually present deregulations of T-lymphocytic immune response. We previously observed …

The Immunoregulatory Actions of DHEA in Tuberculosis, A Tool for Therapeutic Intervention?

B Bongiovanni, A Díaz, N Santucci… - Frontiers in …, 2022 - frontiersin.org
Dehydroepiandrosterone (DHEA) is an androgen synthesized by the adrenal cortex, which
is an intermediary in the biosynthesis of sex hormones, such as testosterone and estradiol …

The dual face of central nervous system tuberculosis: a new Janus Bifrons?

B Sáenz, R Hernandez-Pando, G Fragoso, O Bottasso… - Tuberculosis, 2013 - Elsevier
Tuberculosis (TB) is still a common infectious disease in developing countries, but it is also
re-emerging in industrialized nations due to the HIV/AIDS pandemic. In addition to bacillary …

Exploring immunomodulation by endocrine changes in Lady Windermere syndrome

MR Holt, JJ Miles, WJ Inder… - Clinical & Experimental …, 2019 - academic.oup.com
Lung disease due to nontuberculous mycobacteria (NTM) occurs with disproportionate
frequency in postmenopausal women with a unique phenotype and without clinically …

Increased Frequency of CD4+ CD25+ FoxP3+ T Regulatory Cells in Pulmonary Tuberculosis Patients Undergoing Specific Treatment and Its Relationship with Their …

A Díaz, N Santucci, B Bongiovanni… - Journal of …, 2015 - Wiley Online Library
Tuberculosis (TB) is a major health problem requiring an appropriate cell immune response
(IR) to be controlled. Since regulatory T cells (Tregs) are relevant in IR regulation, we …

Modulation of the phenotype and function of Mycobacterium tuberculosis-stimulated dendritic cells by adrenal steroids

M Angerami, G Suarez, MF Pascutti… - International …, 2013 - academic.oup.com
Cell-mediated immunity, cytokines induced during the specific immune response and T-cell
populations are crucial factors for containing Mycobacterium tuberculosis infection. Recent …

HIV–TB coinfection impairs CD8+ T‐cell differentiation and function while dehydroepiandrosterone improves cytotoxic antitubercular immune responses

GV Suarez, MT Angerami… - European Journal of …, 2015 - Wiley Online Library
Tuberculosis (TB) is the leading cause of death among HIV‐positive patients. The
decreasing frequencies of terminal effector (TTE) CD8+ T cells may increase reactivation …

Tuberculosis vaccination needs to avoid 'decoy'immune reactions

J Ivanyi - Tuberculosis, 2021 - Elsevier
Current search for a new effective vaccine against tuberculosis involves selected antigens,
vectors and adjuvants. These are being evaluated usually by their booster inoculation …