The 2013 ACC/AHA guidelines on blood cholesterol management were a major shift in the
delineation of the main patient groups that could benefit from statin therapy and emphasized …

Statins are the most common drugs administered for patients with cardiovascular disease.
However, due to statin-associated muscle symptoms, adherence to statin therapy is …

Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

Statins are highly effective for preventing cardiovascular events by reducing low-density
lipoprotein cholesterol (LDL-C). However, many patients taking statins report muscle-related …

Statin therapy is generally well tolerated and very effective in the prevention and treatment of
cardiovascular disease, regardless of cholesterol levels; however, it can be associated with …

Statin intolerance is a clinical syndrome whereby adverse effects (AEs) associated with
statin therapy [most commonly statin‐associated muscle symptoms (SAMS)] result in the …

There are currently eight different classes of drugs available for lowering cholesterol levels.
There are currently seven HMG-CoA reductase inhibitors (statins) approved for lowering …

Since the first approval of lovastatin in 1987, hydroxy-methyl-glutaryl CoA (HMG CoA)
reductase inhibitors, or statins, have been effective and widely popular cholesterol-lowering …

Introduction: Statins remain the most commonly prescribed lipid-lowering drug class for the
treatment of atherosclerotic cardiovascular disease. Their well-recognized side effects are …

Statins are the cornerstone of lipid-lowering therapies effective for cardiovascular risk
reduction. Although they are generally well tolerated, statin intolerance (SI) is frequent in …