[HTML][HTML] Scorpion venom peptides: Molecular diversity, structural characteristics, and therapeutic use from channelopathies to viral infections and cancers

Z Xia, D He, Y Wu, HF Kwok, Z Cao - Pharmacological Research, 2023 - Elsevier
Animal venom is an important evolutionary innovation in nature. As one of the most
representative animal venoms, scorpion venom contains an extremely diverse set of …

Scorpion venom as a source of antimicrobial peptides: overview of biomolecule separation, analysis and characterization methods

S Nasr, A Borges, C Sahyoun, R Nasr, R Roufayel… - Antibiotics, 2023 - mdpi.com
Scorpion venoms have long captivated scientific researchers, primarily due to the potency
and specificity of the mechanism of action of their derived components. Among other …

Why to study peptides from venomous and poisonous animals?

AN de Oliveira, AM Soares, SL Da Silva - International Journal of Peptide …, 2023 - Springer
Venom and poison peptides are powerful biological weapons and have proven immense
pharmacological potential because of their high binding affinity to a wide range of molecular …

[HTML][HTML] Antimicrobial potential of scorpion-venom-derived peptides

Z Xia, L Xie, B Li, X Lv, H Zhang, Z Cao - Molecules, 2024 - mdpi.com
The frequent and irrational use of antibiotics by humans has led to the escalating rise of
antimicrobial resistance (AMR) with a high rate of morbidity-mortality worldwide, which …

A critical review of short antimicrobial peptides from scorpion venoms, their physicochemical attributes, and potential for the development of new drugs

PA Fong-Coronado, V Ramirez… - The Journal of …, 2024 - Springer
Scorpion venoms have proven to be excellent sources of antimicrobial agents. However,
although many of them have been functionally characterized, they remain underutilized as …

Effectors of the type VI secretion system have the potential to be modified into antimicrobial peptides

W Lu, H Lu, C Wang, G Wang, W Dong… - Microbiology …, 2023 - Am Soc Microbiol
The use of antibiotics has led to the emergence of multidrug-resistant (MDR) bacteria, and
there is an urgent need to find alternative treatments to alleviate this pressure. The type VI …

Exploration of the Antibacterial and Anti-Inflammatory Activity of a Novel Antimicrobial Peptide Brevinin-1BW

Z Chen, L Wang, D He, Q Liu, Q Han, J Zhang… - Molecules, 2024 - mdpi.com
Antibiotic resistance has emerged as a grave threat to global public health, leading to an
increasing number of treatment failures. Antimicrobial peptides (AMPs) are widely regarded …

Emerging therapeutic applications of scorpion venom peptides in the Middle East and North Africa: A comprehensive review

A Lafnoune, B Darkaoui, A Chbel, IN Irahal - Toxicon, 2025 - Elsevier
The predominantly arid and semi-arid climate, with high temperatures and vast desert areas
in the Middle East and North Africa (MENA) region, creates a favorable environment for …

Profiling the Linear Peptides of Venom from the Brazilian Scorpion Tityus serrulatus: Structural and Functional Characterization

NB Dias, BM de Souza, F Cid-Alda… - Journal of Natural …, 2024 - ACS Publications
Scorpion venoms are a rich source of bioactive peptides, most of which are neurotoxic, with
30 to 70 amino acid residues in their sequences. There are a scarcity of reports in the …

Scorpion Venom Antimicrobial Peptide Derivative BmKn2-T5 Inhibits Enterovirus 71 in the Early Stages of the Viral Life Cycle In Vitro

Z Xia, H Wang, W Chen, A Wang, Z Cao - Biomolecules, 2024 - mdpi.com
Enterovirus 71 (EV71), a typical representative of unenveloped RNA viruses, is the main
pathogenic factor responsible for hand, foot, and mouth disease (HFMD) in infants. This …