Neuroinflammation play an important role in Alzheimer's disease pathogenesis. Advances in
molecular imaging using positron emission tomography have provided insights into the time …

Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Background Sepsis is a potentially fatal disease characterized by acute organ failure that
affects more than 30 million people worldwide. Inflammation is strongly associated with …

Microglial activation plays central roles in neuroinflammatory and neurodegenerative
diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein …

Abstract Neuroligin-4 (NLGN4) loss-of-function mutations are associated with monogenic
heritable autism spectrum disorder (ASD) and cause alterations in both synaptic and …

Neuroinflammation is a significant contributor to Alzheimer's disease (AD). Until now, PET
imaging of the translocator protein (TSPO) has been widely used to depict the neuroimmune …

Efficient treatment of stress-related disorders, such as depression, is still a major challenge.
The onset of antidepressant drug action is generally quite slow, while the anxiolytic action of …

Abstract Background Coronavirus disease 2019 (COVID-19) patients initially develop
respiratory symptoms, but they may also suffer from neurological symptoms. People with …

Cerebral ischemia is a devastating condition that results in impaired blood flow in the brain
leading to acute brain injury. As the most common form of stroke, occlusion of cerebral …

Alzheimer's disease (AD) is the most common neurodegenerative disease and the most
common cause of dementia. Among various pathophysiological aspects, microglia are …