The structure of the human glutaminyl cyclase–SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of …
Recent evidence links the role of human glutaminyl cyclase (hQC) to the amyloidogenic
process involved in Alzheimer's disease (AD). hQC is a zinc enzyme present in neuronal …
process involved in Alzheimer's disease (AD). hQC is a zinc enzyme present in neuronal …
High yield expression and purification of full-length Neurotensin with pyroglutamate modification
K Asadollahi, K Huang, F Yan, LA de Zhang… - Protein Expression and …, 2023 - Elsevier
Abstract Neurotensin (NT) is a 13-residue endogenous peptide found in mammals, with
neurotransmission and hormonal roles in the central nervous system and gastrointestinal …
neurotransmission and hormonal roles in the central nervous system and gastrointestinal …
The soluble Y115E–Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease
F DiPisa, C Pozzi, M Benvenuti, M Andreini… - … Section F: Structural …, 2015 - scripts.iucr.org
Recent developments in molecular pathology and genetics have allowed the identification of
human glutaminyl cyclase (hQC) among the abnormal proteins involved in many …
human glutaminyl cyclase (hQC) among the abnormal proteins involved in many …
[PDF][PDF] Thyrotropin releasing hormone and its cyclised C-terminal peptide inhibit thyroglobulin release from thyroid follicular cells: evidence for acute regulation of …
D Sun, E Garcia, U Raja, L Kindt, DWP Collis… - Research …, 2023 - qmro.qmul.ac.uk
Purpose: Thyrotropin releasing hormone (TRH), a tripeptide hormone produced in the
hypothalamus, controls thyroid stimulating hormone (TSH) production from the pituitary …
hypothalamus, controls thyroid stimulating hormone (TSH) production from the pituitary …
AnaSpec Launches Industry's First Fluorimetric Assay for Measuring Glutaminyl Cyclase Activity
S Thomas - selectscience.net
AnaSpec is pleased to announce the release of the first commercially available 96-well
format, fluorimetric assay for measuring Glutaminyl Cyclase (QC) activity-the SensoLyte® …
format, fluorimetric assay for measuring Glutaminyl Cyclase (QC) activity-the SensoLyte® …