COVID-19 is an infectious disease caused by Coronavirus 2 (SARS-CoV-2) that may lead to
a severe acute respiratory syndrome. Such syndrome is thought to be related, at least in …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes
coronavirus disease 2019 (COVID-19) and can be associated with serious complications …

OBJECTIVE: As N-acetylcysteine (NAC) is promising as a re-purposed drug for the
adjunctive or supportive treatment of serious COVID-19, this article aimed to describe …

The airway epithelial glycocalyx plays an important role in preventing severe acute
respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial …

Over the last decade, the management of acute respiratory distress syndrome (ARDS) has
made considerable progress both regarding supportive and pharmacologic therapies. Lung …

The aim of this study was to evaluate the effect and safety of N‐acetylcysteine (NAC)
inhalation spray in the treatment of patients with coronavirus disease 2019 (COVID‐19). This …

There is a possible role for oxidative stress, a state characterized by an altered balance
between the production of free radicals or reactive oxygen species (ROS) and antioxidant …

Objectives: Recent clinical studies suggest that oxidative stress is one of the key players in
the pathogenesis of coronavirus disease 2019 (COVID-19), and N-acetylcysteine (NAC), a …

Alveolar macrophages (AMs) are the drivers of pulmonary cytokine storm in severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed to investigate …

The coronavirus disease (COVID-19) pandemic is a leading global health and economic
challenge. What defines the disease's progression is not entirely understood, but there are …