In the fatal disease—amyotrophic lateral sclerosis (ALS)—upper (corticospinal) motor
neurons (MNs) and lower somatic MNs, which innervate voluntary muscles, degenerate …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the
death of both upper and lower motor neurons (MNs) in the brain, brainstem and spinal cord …

It is widely recognized that the neural basis of brain function can be fully understood only by
integrating many disciplines at many levels. Studies of synaptic organization are bringing …

Drawing on the disciplines of neurophysiology and physics, Neuromechanics of Human
Movement, Fourth Edition, explores how the nervous system controls the actions of muscles …

Movement is accomplished by the controlled activation of motor unit populations. Our
understanding of motor unit physiology has been derived from experimental work on the …

Skeletal Muscle: Form and Function, Second Edition, provides readers with a detailed
understanding of the different facets of muscle physiology. Meticulously researched and …

Respiratory activities are produced by medullary respiratory rhythm generators and are
modulated from various sites in the lower brainstem, and which are then output as motor …

Voluntary movement requires communication from cortex to the spinal cord, where a
dedicated pool of motor units (MUs) activates each muscle. The canonical description of MU …

Lee, RH and CJ Heckman. Bistability in spinal motoneurons in vivo: systematic variations in
persistent inward currents. J. Neurophysiol. 80: 583–593, 1998. Bistable behavior in spinal …

The size and branching structure of the dendritic tree were studied in nine type‐identified
triceps surae α‐motoneurons that were labeled intracellularly with horseradish peroxidase …