Aminolevulinic acid (ALA) is the first metabolite in the heme biosynthesis pathway in
humans. In addition to the end product heme, this pathway also produces other porphyrin …

Melanoma is the most dangerous form of skin cancer, with a steeply rising incidence and a
poor prognosis in its advanced stages. Melanoma is highly resistant to traditional …

5-Aminolevulinic acid (ALA) is a naturally occurring amino acid synthesized in all nucleated
mammalian cells. As a porphyrin precursor, ALA is metabolized in the heme biosynthetic …

Photosensitizer protoporphyrin IX (PpIX) fluorescence, intracellular localization and cell
response to photodynamic therapy (PDT) were analyzed in MCF10A normal breast …

Three 2-(morpholin-4-yl) ethoxy substituted phthalocyanines were synthesized and
characterized. Phthalocyanine derivatives revealed moderate to high quantum yields of …

It is more than sixty years since the era of modern photodynamic therapy (PDT) for cancer
began. Enhanced selectivity for malignant cells with a reduced selectivity for non-malignant …

Aminolevulinic acid (ALA) has been approved by the US FDA for fluorescence-guided
resection of high-grade glioma and photodynamic therapy (PDT) of superficial skin …

Malignant melanoma (MM) continues to claim millions of lives around the world due to its
limited therapeutic alternatives. Photodynamic therapy (PDT) has gained popularity in …

We aimed to investigate the role of the ABCG2 transporter in the efficacy of sonodynamic
therapy (SDT) with Photofrin in the glioma stem-like cells (GSCs) isolated and cultured from …

Background Cutaneous melanoma represents the most lethal form of skin cancer and
remains refractory to current therapies. Failure of treatment has been attributed to the over …