Advances in the carbonic anhydrase (CA, EC 4.2. 1.1) research over the last three decades
are presented, with an emphasis on the deciphering of the activation mechanism, the …

Carbonic anhydrases (CAs, EC 4.2. 1.1) are ubiquitous metallo-enzymes, present
throughout most living organisms and encoded by five evolutionarily unrelated gene …

Carbonic anhydrases (CAs), a group of ubiquitously expressed metalloenzymes, are
involved in numerous physiological and pathological processes, including …

Carbonic anhydrase (CA, EC 4.2. 1.1) is a protein that is especially well-suited to serve as a
model in many types of studies in biophysics, bioanalysis, the physical-organic chemistry of …

Carbonic Anhydrase: Its Inhibitors and Activators provides a state-of-the-art overview of the
latest developments and challenges in carbonic anhydrase research. Authors describe the …

The Neurovascular Unit (NVU) is an important multicellular structure of the central nervous
system (CNS), which participates in the regulation of cerebral blood flow (CBF), delivery of …

Mammalian carbonic anhydrases (CAs; EC 4.2. 1.1) of which 16 isoforms are known, are
involved in important physiological functions. Their inhibition is exploited pharmacologically …

Inhibitors and activators of the zinc enzyme carbonic anhydrase (CA, EC 4.2. 1.1) have a
large number of applications in therapy. Many types of such new derivatives have been …

Carbonic anhydrases (CAs, EC 4.2. 1.1) are inhibited by sulfonamides, phenols, and
coumarins. Polyamines such as spermine, spermidine, and many synthetic congeners are …

In this study, 4‐[5‐aryl‐3‐(thiophen‐2‐yl)‐4, 5‐dihydro‐1H‐pyrazol‐1‐yl]
benzenesulfonamides were synthesized, and inhibition effects on AC hE, hCA I, and hCA II …