Excessive adiposity raises blood pressure and accounts for 65–75% of primary
hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity …

Renal sympathetic (efferent) nerves play an important role in the regulation of renal function,
including glomerular filtration, sodium reabsorption, and renin release. The kidney is also …

Obesity is reaching epidemic proportions globally and represents a major cause of
comorbidities, mostly related to cardiovascular disease. The autonomic nervous system …

Despite availability of effective drugs for hypertension therapy, significant numbers of
hypertensive patients fail to achieve recommended blood pressure levels on≥ 3 …

The objective of this review is to provide an in‐depth evaluation of how renal nerves
regulate renal and cardiovascular function with a focus on long‐term control of arterial …

The prevalence of obesity has tripled over the past five decades. Obesity, especially visceral
obesity, is closely related to hypertension, increasing the risk of primary (essential) …

Renal denervation (RDNX) lowers mean arterial pressure (MAP) in patients with resistant
hypertension. Less well studied is the effect of celiac ganglionectomy (CGX), a procedure …

The (pro) renin receptor (PRR) was originally cloned as a specific single-transmembrane
receptor for prorenin and renin and has now emerged as a multifunctional protein implicated …

The nervous and immune systems both serve as essential assessors and regulators of
physiological function. Recently, there has been a great interest in how the nervous and …

Background and Purpose All previous rodent models lacking the peptide hormone
angiotensin II (Ang II) were hypotensive. A mixed background strain with global deletion of …