Obesity and COVID-19: molecular mechanisms linking both pandemics

A Ritter, NN Kreis, F Louwen, J Yuan - International journal of molecular …, 2020 - mdpi.com
The coronavirus disease 2019 COVID-19 pandemic is rapidly spreading worldwide and is
becoming a major public health crisis. Increasing evidence demonstrates a strong …

[HTML][HTML] Epidemiology and pathogenesis of heart failure with preserved ejection fraction

N Nair - Reviews in cardiovascular medicine, 2020 - imrpress.com
Heart failure (HF) is a complex syndrome that affects approximately 6.5 million adults in the
United States. About half of the 6.5 million adults with HF are estimated to be individuals with …

Oxidative stress and antioxidative therapy in pulmonary arterial hypertension

D Xu, YH Hu, X Gou, FY Li, XYC Yang, YM Li, F Chen - Molecules, 2022 - mdpi.com
Pulmonary arterial hypertension (PAH) is clinically characterized by a progressive increase
in pulmonary artery pressure, followed by right ventricular hypertrophy and subsequently …

Obesity and cardiovascular disease: An executive document on pathophysiological and clinical links promoted by the Italian Society of Cardiovascular Prevention …

M Volpe, G Gallo - Frontiers in Cardiovascular Medicine, 2023 - frontiersin.org
The prevalence of obesity worldwide has increased in recent decades not only among
adults, but also in children and adolescents. This phenomenon contributes to an increased …

Obesity blunts the ventilatory response to exercise in men and women

BN Balmain, QM Halverson, AR Tomlinson… - Annals of the …, 2021 - atsjournals.org
Rationale: Obesity presents a mechanical load to the thorax, which could perturb the
generation of minute ventilation (V̇e) during exercise. Because the respiratory effects of …

Current understanding of molecular pathophysiology of heart failure with preserved ejection fraction

H Budde, R Hassoun, A Mügge, Á Kovács… - Frontiers in …, 2022 - frontiersin.org
Heart Failure (HF) is the most common cause of hospitalization in the Western societies. HF
is a heterogeneous and complex syndrome that may result from any dysfunction of systolic …

Emerging therapies: Potential roles of SGLT2 inhibitors in the management of pulmonary hypertension

T Luo, H Wu, W Zhu, L Zhang, Y Huang, X Yang - Respiratory Medicine, 2024 - Elsevier
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

Pulmonary hypertension due to high cardiac output

KN Qaiser, S Sahay, AR Tonelli - Respiratory medicine, 2023 - Elsevier
Pulmonary hypertension (PH) is usually associated with a normal or decreased cardiac
output (CO). Less commonly, PH can occur in the context of a hyperdynamic circulation …

Obesity, systemic hypertension, and pulmonary hypertension: a tale of three diseases

A Wahab, AK Dey, D Bandyopadhyay… - Current Problems in …, 2021 - Elsevier
Cardiovascular disease (CVD), especially ischemic heart disease and stroke, is the major
cause of death worldwide, accounting for more than one-third of all deaths annually …

Impact of malnutrition on prognosis in patients with pulmonary arterial hypertension

M Nakashima, S Akagi, K Ejiri… - Pulmonary …, 2023 - Wiley Online Library
Pulmonary arterial hypertension is a life‐threatening disease that coexists with right heart
failure. We evaluated the relationship between malnutrition and prognosis in patients with …