This review discusses current understanding of the role that endogenous and exogenous
progenitor cells may have in the treatment of the diseased heart. In the last several years, a …

Stem cells share several characteristics of cancer cells including loss of contact inhibition
and immortality. Therefore, stem cells represent an excellent model system in which to …

Human embryonic stem (ES) cells offer substantial opportunities for providing well-defined
differentiated cells for drug discovery, toxicology, and regenerative medicine, but the …

Human embryonic stem (hES) cells are pluripotent cells derived from the inner cell mass
cells of blastocysts with the potential to maintain an undifferentiated state indefinitely. Fully …

Mesenchymal stem cells (MSCs) represent a new tool for delivery of therapeutic agents to
tumor cells. In this study, we have evaluated the anti‐tumor activity of human MSCs stably …

The mammalian blastocyst is the source of the most pluripotent stem cells known: embryonic
stem (ES) cells. However, ES cells are not totipotent; in mouse chimeras, they do not …

Energy metabolism is intrinsic to cell viability but surprisingly has been little studied in
human embryonic stem cells (hESCs). The current study aims to investigate the effect of …

We induced neural cells by treating cynomolgus monkey embryonic stem (ES) cells with
retinoic acid. The treated cells mainly expressed βIIItubulin. They further differentiated into …

Stem cells, while difficult to define, hold great promise as tools for understanding
development and as therapy. However, this difficulty in defining stem cells has led to a …

Recent evidence would suggest that the heart is not a terminally differentiated organ and
has the ability to regenerate itself under normal and pathophysiologic conditions. A major …