Over the last few years, organic bioelectronics has experienced an exponential growth with
applications encompassing platforms for tissue engineering, drug delivery systems …

Myocardial infarctions are one of the most common forms of cardiac injury and death
worldwide. Infarctions cause immediate necrosis in a localized region of the myocardium …

Over the last decade, Organ-on-Chip (OoC) emerged as a promising technology for
advanced in vitro models, recapitulating key physiological cues. OoC approaches tailored …

After a myocardial infarction, the boundary between the injured, hypoxic tissue and the
adjacent viable, normoxic tissue, known as the border zone, is characterized by an oxygen …

Cardiac two-dimensional tissues were engineered using biomimetic micropatterns based on
the fibronectin-rich extracellular matrix (ECM) of the embryonic heart. The goal of this …

Many cardiovascular diseases are associated with pathological remodeling of the
extracellular matrix (ECM) in the myocardium. ECM remodeling is a complex, multifactorial …

Contraction of cardiac myocytes depends on energy generated by the mitochondria. During
cardiac development and disease, the structure and function of the mitochondrial network in …

A standard culture of cardiac cells as unorganized monolayers on tissue culture plastic or
glass does not recapitulate the architectural or the mechanical properties of native …

Human pluripotent stem cell‐derived cardiomyocytes (hPSC‐CMs) have emerged as an
exciting new tool for cardiac research and can serve as a preclinical platform for drug …

In ventricular myocardium, extracellular matrix (ECM) remodeling is a hallmark of
physiological and pathological growth, coincident with metabolic rewiring of cardiac …