Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …

Protein aggregation is the main hallmark of neurodegenerative diseases. Many proteins
found in pathological inclusions are known to undergo liquid-liquid phase separation, a …

Aggregation of alpha-synuclein (α-Syn) drives Parkinson's disease (PD), although the initial
stages of self-assembly and structural conversion have not been directly observed inside …

Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Fluorescence monitoring of ATP in different organelles is now feasible with a few biosensors
developed, which, however, show low sensitivity, limited biocompatibility, and accessibility …

Persisters are dormant phenotypic variants of bacterial cells that are tolerant to killing by
antibiotics 1. Persisters are associated with chronic infections and antibiotic treatment failure …

The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

Loss of proteostasis underlies ageing and neurodegeneration characterized by the
accumulation of protein aggregates and mitochondrial dysfunction,,,,. Although many …

Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit
immune responses specific for dead cell-associated antigens. However, multiple stimuli can …

The integrity of myelinated axons relies on homeostatic support from oligodendrocytes
(OLs). To determine how OLs detect axonal spiking and how rapid axon–OL metabolic …